Publications

Here you will find an overview of our publications over the last ten years. As a group, we strive towards open access publishing, so most of our papers are published open access and can be accessed via the publishers. We store prints and preprints at Radboud Repository. All other papers are available on request via GUTS.pa@radboudumc.nl.

2025

AS Oguz Erdogan, F Simmer, ID Nagtegaal. Tumor deposits should not be placed in the M category of TNM: a comparative survival analysis using SEER Data. Int J Cancer 2025, 156(2): 274-279
S van de Weerd, A Torang, I. van den Berg, V Lammers, S van den Bergh, JH de Jong, G van Bochove, S van Hooff, N Brouwer, ID Nagtegaal, M Koopman, G Vink, F van der Baan, H van Krieken, J Koster, J Ijzermans, JML Roodhart, JP Medema. Benefit of adjuvant chemotherapy on recurrence free survival per consensus molecular subtype in stage III colon cancer. Int J Cancer, 2025, 156(2): 456-466
J Miyoshi, F Gao, S Toden, M Scarpa, T Whitsett, LJ Inge, RM Bremner, T Takayma, Y Cheng, T Bottiglieri, ID Nagtegaal, MJ Shrubsole, AH Zaidi, X Wang, HG Coleman, LA Anderson, SJ Meltzer, A Goel. A liquid biopsy to identify Barrett’s esophagus, dysplasia and esophageal adenocarcinoma: the Emerald multi-center study. Gut, in press
TS Haddad, JM Bokhorst, M Berger, L van den Dobbelsteen, F Simmer, J Galon, JAWM van der Laak, F Paget, I Zlobec, A Lugli, ID Nagtegaal. Combining immunoscore and tumor budding: a powerful prognostication based on the tumor-host interface. J Transl Med, in press
SK Öztürk, JM Bokhorst, E Baumann, K Sheahan, CJH van de Velde, CAM Marijnen, GAP Hospers, M Doukas, M Vieth, A Lugli, ID Nagtegaal. Exploring intratumoral budding in colorectal cancer using computational pathology: a biopsy- based evaluation. Modern Path, in press
BJ van Stigt, I Lansdorp-Vogelaar, MCW Spaander, AJ van Vuuren, E Dekker, FJ van Kemenade, ID Nagtegaal, ME van Leerdam, E Toes-Zoutendijk. Risk stratification in FIT-based colorectal cancer screening: interval cancer risk after the upper age limit of screening has been reached. Int J Cancer, in press
NPM Brouwer, S van Vliet, J. IntHout, JHW de Wilt, F Simmer, N Hugen, ID Nagtegaal. Tumour deposits are associated with worse survival than extranodal extension; a network meta-analysis on tumor nodules in colorectal cancer. Histopathology, in press
E Toes-Zoutendijk, L de Jonge, CA van Iersel, MCW Spaander, AJ van Vuuren, FJ van Kemenade, C Ramakers, E Dekker, ID Nagtegaal, ME van Leerdam, I Lansdorp-Vogelaar. Impact of delayed screening invitations on detected and interval cancers in the Dutch colorectal cancer screening program: individual-level data analysis. Gut, in press
L Elze, RS van der Post, JR Vos, AR Mensenkamp, S Pamidimarri Naga, JE Hampstead, E Vermeulen, M Oorsprong, T Hofste, M Simons, ID Nagtegaal, N Hoogerbrugge, RM de Voer, MJL Ligtenberg. Genomic instability in non-breast/ovarian malignancies of individuals with germline pathogenic variants in BRCA1/2. J Natl Cancer Inst, in press
E Toes-Zoutendijk, HJ van der Schootbrugge-Vandermeer, MA Katsara, L de Jonge, MCW Spaander, AJ van Vuuren, FJ van Kemenade, E Dekker, ID Nagtegaal, ME van Leerdam, I Lansdorp-Vogelaar, RGS Meester. Harm-to-benefit ratio of fecal immunochemical test-based screening for colorectal cancer given prior fecal hemoglobin concentrations. Clin Gastrol Hepatol, in press
M te Groen, MEW Derks, ID Nagtegaal, CP Peters, AC de Vries, G Dijkstra, TEH Romkens, CS Horjus, NK de Boer, ME de Jong, B van Ruijven, F Hoentjen,S Vos, LAAP Derikx. Gastrointestinal consensus of revised high-grade dysplasia in IBD impacts the advanced neoplasia rate: a multicenter cohort study. Eur J Gastrol Hepatol, in press
F Jacobs, V Groenhuis, IM de Jong, ID Nagtegaal, MM Rovers, GJ Bulte, JJ Futterer. Evaluation of a Novel Forward-Looking Optical Coherence Tomography Probe for Endoscopic Applications: an Ex Vivo Feasibility Study. Surg Endo, in press
SG van Ravensteijn, JJ de Haan, HGelderblom, MJL Nederkoorn, MHS Hillebrandt-Roeffen, MAJ Gorris, TJJ de Bitter, A Boleij, A Gusinac, THA Ederveen, UE Flucke, JJ Bonenkamp, FM Speetjens, SEJ Kaal, MSmits, KF Bol, CML van Herpen, YMH Versleijen-Jonkers, IME Desar. Cemiplimab in locally advanced or metastatic secondary angiosarcomas (CEMangio): A phase II clinical trial and biomarker analyses. 2025; 31 (17): 3678-3691
Laurence Zitvogel, Lisa Derosa, Bertrand Routy, Sibylle Loibl, Lucie Heinzerling, I Jolanda M de Vries, Lars Engstrand, Nicola Segata, Guido Kroemer, ONCOBIOME network. Impact of the ONCOBIOME network in cancer microbiome research. Nature Medicine, 2025 31: 1085–1098
Kemp LJS, Monster JL, Wood CS, Moers M, Vliem MJ, Khalil AA, Jamieson NB, Brosens LAA, Kodach LL, van Dieren JM, Bisseling TM, van der Post RS, Gloerich M. Tumour-intrinsic alterations and stromal matrix remodelling promote Wnt-niche independence during diffuse-type gastric cancer progression. Gut. 2025: gutjnl-2024-334589.
Peeters E, van Genugten EAJ, Heskamp S, de Vries IJM, van Herpen C, Koenen HJPM, Kneilling M, van der Post RS, van Dop WA, Westdorp H, Aarntzen E. Exploring molecular imaging to investigate immune checkpoint inhibitor-related toxicity. J Immunother Cancer. 2025; 13(5): e011009.
Hendricks LAJ, Verbeek KCJ, Schuurs-Hoeijmakers JHM, de Jong MM, Links TP, Brems H, Aerden M, Brunet J, Lleuger-Pujol R, Hüneburg R, Aretz S, Colas C, Villy MC, Woodward ER, Evans DG, Bosch DGM, Donze SH, Foretová L, Blatnik A, Leter EM, Tischkowitz M, Jahn A, de Putter R, Dupont J, Briskemyr S, Steinke-Lange V, Baldassarri M, Anastasiadou VC, Irmejs A, Oliveira C, van der Post RS, Mensenkamp AR, Tesi B, Mu N, Benusiglio PR, Gerasimenko A, Innella G, Turchetti D, Houdayer C, Branchaud M, Høberg-Vetti H, Haavind MT, Balmaña J, Torres M, Genuardi M, Panfili A, Jørgensen K, Mæhle L, Hoogerbrugge N, Vos JR. The risk of a second primary cancer in PTEN Hamartoma Tumor Syndrome (PHTS). Genet Med. 2025: 101467.
Hinić S, Mensenkamp AR, Schuurs-Hoeijmakers JHM, Brugnoletti F, Vreede L, van Veen EM, Mijzen B, van der Post RS, Genuardi M, Ligtenberg MJL, Hoogerbrugge N, de Voer RM. Exome-based cancer predisposition gene testing can provide a genetic diagnosis for individuals with heterogeneous tumor phenotypes. Eur J Hum Genet. 2025; 33(6): 803-809.
Hendricks LAJ, Verbeek KCJ, Schuurs-Hoeijmakers JHM, de Putter R, Brems H,Van Daele SH, Anastasiadou VC, Foretová L, Benusiglio PR, Gerasimenko A, ColasC, Villy MC, Houdayer C, Branchaud M, Hüneburg R, Aretz S, Jahn A, Steinke-LangeV, Innella G, Turchetti D, Barili V, Genuardi M, Panfili A, Baldassarri M, Irmejs A, de Jong MM, Links TP, Leter EM, Bosch DGM, Donze SH, van der Post RS, Mensenkamp AR, Westdorp H, Høberg-Vetti H, Tveit Haavind M, Jørgensen K, MæhleL, Briskemyr S, Garcia JD, Blatnik A, Balmaña J, Torres M, Brunet J, Lleuger-Pujol R, Tham E, Tischkowitz M, Evans DG, Hyder Z, Hoogerbrugge N, Vos JR. Cancer prognosis and treatment results in patients with PTEN Hamartoma Tumour Syndrome (PHTS)-a European cohort study. BJC Rep. 2025; 3(1): 42.
Schei-Andersen AJ, Schuurs-Hoeijmakers JHM, van der Post R, Mensenkamp AR, Schieving J; PTEN Study Group; Vos JR, Hoogerbrugge N. Deep Phenotyping of Pathology-Confirmed Benign Lesions in PTEN Hamartoma Tumor Syndrome Patients. Clin Genet. 2025.
Weijers DD, Hinić S, Kroeze E, Gorris MA, Schreibelt G, Middelkamp S, Mensenkamp AR, Bladergroen R, Verrijp K, Hoogerbrugge N, Wesseling P, van der Post RS, Loeffen JL, Gidding CE, van Kouwen MC, de Vries IJM, van Boxtel R, de Voer RM, Jongmans MC, Kuiper RP. Unraveling mutagenic processes influencing the tumor mutational patterns of individuals with constitutional mismatch repair deficiency. Nat Commun. 2025; 16(1): 4459.

2024

NPM Brouwer, A Khan, JM Bokhorst, F Ayatollahi, J Hay, F Ciompi, F Simmer, N Hugen, JHW de Wilt, MD Berger, A Lugli, I Zlobec, J Edwards, ID Nagtegaal. The complexity of shapes; how the circularity of tumor nodules impacts prognosis in colorectal cancer. Modern Pathol 2024, 37(1): 100376
NPM Brouwer, AAS Oguz Erdogan, S van Vliet, N Rutgers, N Knijn, G van Lijnschoten, JJ Tan, JHW de Wilt, N Hugen, G Brown, F Simmer, ID Nagtegaal. Unraveling the routes to distant metastases in colorectal cancer: Tumor deposits and lymph node metastases as the gateway. Cancer Comm 2024, 44(10): 1209-1213
H Kayhanian, W Cross, SEM van der Horst, P Barmpoutis, E Lakatos, G Caravagna, L Zapata, A van Hoeck, S Middelkamp, K Litchfield, C Steele, W Waddingham, D Patel, S Milite, C Jin, AM Baker, D Alexander, K Khan, D Hochhauser, M Novelli, B Werner, R van Boxtel, JH Hageman, JR Buissant des Amorie, J Linares, MJL Ligtenberg, ID Nagtegaal, MM Lacle, Moons, LMG, LAA Brosens, N Pillay, A Sottoriva, TA Graham, M Rodriguez-Justo, KK Shiu, HJG Snippert, M Jansen. Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer. Nature Med 2024, 56(7): 1420-1433
ME Vink-Börger, M den Bakker, Q Voorham, F van Nederveen, ID Nagtegaal. Mismatch repair deficiency: how reliable is the two-antibody approach? A national real-life study. Histopath 2024, 85: 639-648
F Baas, N Brusselaers, ID Nagtegaal, L Engstrand, A Boleij. Navigating beyond associations: opportunities to establish causal relationships between the gut microbiome and colorectal cancer. Cell host Microbe 2024, 32(8): 1235-1247
ME Vink-Börger, P Dabir, J Krekels, M van Kouwen, RS van der Post, ID Nagtegaal. Deficient mismatch repair screening of advanced adenomas in the population screening program for colorectal cancer is not effective. Histopathology, 2024, 84 (6): 1056-1060
S Kus Öztürk, C Graham Martinez, C Verhoef, M Tosetto, K Sheahan, GAP Hospers, CJH van de Velde, CAM Marijnen, RS van der Post, ID Nagtegaal. Lymph node regression after neoadjuvant therapy in rectal cancer. Histopathology, 2024, 84(6): 935-946
N Hugen, QJM Voorham, GL Beets, M Loughrey, P Snaebjornsson, ID Nagtegaal. The mode of circumferential margin involvement determines its impact on outcomes: a population based study. Eur J Surg Oncol 2024, 50: 108598
Smits LJH, Siebers AG, Lissenberg-Witte BI, Lansdorp-Vogelaar I, van Kouwen MCA, Tuynman JB, van Grieken NCT, Nagtegaal ID. Risk factors for advanced colorectal neoplasia and colorectal cancer detected at surveillance: a nationwide study in the modern era. Histopath 2024, 85: 627-638
Vos AM, Pijnenborg L, van Vliet S, Kodach LL, Ciompi F, van der Post RS, Simmer F, Nagtegaal ID. Biological background of colorectal polyps and carcinomas with heterotopic ossification: A national study and literature review. Human Path 2024, 145: 34-41
MEW Derks, LMA van Lierop, M te Groen, CCHJ Kuijpers, ID Nagtegaal, F Hoentjen. Long-term impact of the COVID-19 pandemic on Inflammatory Bowel Disease healthcare utilisation: a two-year nationwide update. IBD 2024, 30(1): 146-149
E Toes-Zoutendijk, ECH Breekveldt, L van der Schee, ID Nagtegaal, MAG Elferink, I Lansdorp-Vogelaar, LMG Moons, ME van Leerdam. Differences in treatment of stage I CRCs: a population-based study of CRCs detected within and outside screening. Endoscopy 2024, 56(1): 5-13
C Woortman, GJLH van Leenders, N Hugen, MGH van Oijen, ID Nagtegaal. Origin and outcome of metastatic tumors to the testes: a nationwide study. BJU Int 2024, 133: 305-313
H Dawson,JM Bokhorst, L Studer, M Vieth, A Oguz Erdogan, S Kus Öztürk, R Kirsch, S Brockmoeller, G Cathomas, R Buslei, D Fink, M Roumet, I Zlobec, J van der Laak, ID Nagtegaal, A Lugli. Lymph node metastases and recurrence in pT1 colorectal cancer: prediction with the International Budding Consortium Score – a retrospective multi-centric study. UEGJ 2024, 12(3): 299-308
WH Zwart, SJD Temmink, GAP Hospers, CAM Marijnen, H Putter, ID Nagtegaal, LK Blomqvist, E Meershoek-Klein Kranenbarg, AGH Roodvoets, A Martling, CJH van de Velde, B Glimelius, KCMJ Peeters, B van Etten, PJ Nilsson. Oncological outcomes after a pathological complete response following total neoadjuvant treatment or chemoradiotherapy for high-risk locally advanced rectal cancer in the RAPIDO trial. EJC 2024, 204: 114044
G Zaffaroni, A Mannucci, L Koskenvuo, B de Lacy, A Maffioli, T Bisseling, E Half, GM Cavestro, L Valle, N Ryan, S Aretz, K Brown, F Buttitta, F Carneiro, O Claber, R Blanco-Colino, M Collard, E Crosbie, M Cunha, T Doulias, C Fleming, H Heinrich, R Hüneburg, J Metras, ID Nagtegaal, I Negoi, M Nielsen, G Pellino, L Ricciardiello, A Sagir, L Sánchez-Guillén, TT Seppälä, P Siersema, B Striebeck, RJ Sampson, A Latchford, Y Parc, J Burn, G Möslein. Updated European guidelines for clinical management of familial adenomatous polyposis (FAP), MUTYH-associated polyposis (MAP), gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS), and other rate adenomatous polyposis syndromes: a joint EHTG-ESCP revision. BJS 2024, 111(5); znae070
MEW Derks, M te Groen, LMA van Lierop, S Murthy, DT Rubin, T Bessissow, ID Nagtegaal, WA Bemelman, LAAP Derikx, F Hoentjen. Management of colorectal neoplasia in IBD patients: current practice and future perspectives. J Crohn Colitis 2024, 18(10): 1726-1735
IH Mast, JHW de Wilt, B Duman, KC Smit, EC Gootjes, PAJ Vissers, H Rütten, ID Nagtegaal, MTE Hopman, AM May, LM Buffart. Physical activity at diagnosis is associated with tumor downstaging after neoadjuvant chemoradiotherapy in patients with rectal cancer. Rad Oncol 2024, 110523
DJ Höppener, W Aswolinskiy, D Tellez, Z Qian, PMH Nierop, ID Nagtegaal, M Doukas, JHW de Wilt, DJ Grünhagen, JAWM van der Laak, P Vermeulen, F Ciompi, C Verhoef. Classifying histopathological growth patterns for resected colorectal liver metastases on whole slide imaging with deep learning. BJS open 2024, 8(6): zrae127
S Aherne, ÉJ Ryan, MG Davey, B Creavin, A McCarthy, R Geraghty, D Gibbons, ID Nagtegaal, A Lugli, R Kirsch, ST Martin, DC Winter, K Sheahan. Tumour Budding as a prognostic biomarker in biopsies and resections of neoadjuvant –treated rectal adenocarcinoma. Histopathology 2024, 85(2): 224-243
M te Groen, M Derks, N den Broeder, C Peters, G Dijkstra, A de Vries, T Romkens, C Horjus, N de Boer, M de Jong, ID Nagtegaal, LAAP Derikx, F Hoentjen. Quality of surveillance impacts the colitis-associated advanced neoplasia risk: a multicenter case-control study. Clin Gastrol Hepatol 2024, 22(2): 357-367
F Kazemzadeh, JAA Snoek, QJ Voorham, MGH van Oijen, N Hugen, ID Nagtegaal. Association of metastatic pattern in breast cancer with tumor and patient specific factors: a nationwide autopsy study using artificial intelligence. Breast cancer 2024, 31(2): 263-271
N Rolleman, W Klein, ID Nagtegaal, MJAM van Putten, I de Blaauw, S Botden. Comparing surface electroenterography measurements between patients suffering from Hirschsprung’s disease and controls. Scientific Rep 2024, 24: 3585.
S Puttmann, L Borras Ferris , N Marini, Wi Aswolinsky, S Vatrano , F Fragetta , ID Nagtegaal, RS van der Post , F Ciompi , M Atzori, C Friedrich, H Muller. Automated classification of celiac disease in histopathological images: a multi-scale approach. SPIE Proc 2024, 12927
KK Iyer, D Poel, A Miggelenbrink,W Kerkhof, J Janssen, L Bakkerus, L de Jong,E van den Hombergh, ID Nagtegaal, DVF Tauriello, NP van Erp, HMW Verheul. High-dose short-term osimertinib treatment is effective in patient-derived metastatic colorectal cancer organoids. BJC Reports 2024, 2(1): 29
Fiegl A, Wendler O, Giedl J, Gaisa NT, Richter G, Campean V, Burger M, Simmer F, Nagtegaal I, Wullich B, Bertz S, Hartmann A, Stoehr R. Elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) in penile squamous cell carcinoma – no evidence for a role in carcinogenesis. Curr Oncol 2024, 31: 5752-5761
Bakkerus L, Subtil B, Bontkes HJ, Gootjes EC, Reijm M, Vullings M, Verrijp K, Bokhorst JM, Woortman C, Nagtegaal ID, Jonker MA, van der Vliet HJ, Verhoef C, Gorris MAJ, de Vries IJM, de Gruijl TD, Verheul HMW, Buffart TE, Tauriello DVF. Exploring immune status in peripheral blood and tumor tissue in association with survival in patients with multi-organ metastatic colorectal cancer. Oncoimmunology 2024;13(1):2361971.
Monster JL, Kemp LJ, Busslinger GA, Vliem MJ, Derks LL, Staes AA, Bisseling TM, Clevers H, van der Post RS, Gloerich M. Cell division-dependent dissemination following E-cadherin loss underlies initiation of diffuse-type gastric cancer. J Pathol. 2024; 263(2): 226-241.
Hinić S, Cybulski C, Van der Post RS, Vos JR, Schuurs-Hoeijmakers J, Brugnoletti F, Koene S, Vreede L, van Zelst-Stams WAG, Kets CM, Haadsma M, Spruijt L, Wevers MR, Evans DG, Wimmer K, Schnaiter S, Volk AE, Möllring A, dePutter R, Soikkonen L, Kahre T, Tooming M, de Jong MM, Vaz F, Mensenkamp AR, Genuardi M, Lubinski J, Ligtenberg M, Hoogerbrugge N, de Voer RM. The heterogeneous cancer phenotype of individuals with biallelic germline pathogenic variants in CHEK2. Genet Med. 2024; 26(5): 101101.
Hinić S, van der Post RS, Vreede L, Schuurs-Hoeijmakers J, Koene S, Jansen EAM, Bervoets-Metge F, Mensenkamp AR, Hoogerbrugge N, Ligtenberg MJL, de Voer RM. The genomic landscape of breast and non-breast cancers from individuals with germline CHEK2 deficiency. JNCI Cancer Spectr. 2024; 8(4): pkae044.
van der Sluis L, van Dieren JM, van der Post RS, Bisseling TM. Current advances and challenges in Managing Hereditary Diffuse Gastric Cancer (HDGC): a narrative review. Hered Cancer Clin Pract. 2024; 22(1): 21.
Schei-Andersen AJ, Hendricks LAJ, van der Post RS, Mensenkamp AR, Schieving J; PTEN Study Group; Schuurs-Hoeijmakers JHM, Hoogerbrugge N, Vos JR. Histopathological phenotyping of cancers in PTEN Hamartoma Tumor Syndrome for improved recognition: A single-center study. Int J Cancer. 2024; 155(9): 1567-1576.
van Dooren M, de Savornin Lohman EAJ, van der Post RS, Erdmann JI,Hoogwater FJH, Groot Koerkamp B, van den Boezem PB, de Reuver PR. Referral rateof patients with incidental gallbladder cancer and survival: outcomes of amulticentre retrospective study. BJS Open. 2024; 8(2): zrae013.
Gertsen EC, van der Veen A, Brenkman HJF, Brosens LAA, van der Post RS, Verhoeven RHA, Luijten JCHBM, Vissers PAJ, Vegt E, van Hillegersberg R, Siersema PD, Ruurda JP. Multimodal Therapy Versus Primary Surgery for Gastric and Gastroesophageal Junction Diffuse Type Carcinoma, with a Focus on Signet Ring Cell Carcinoma: A Nationwide Study. Ann Surg Oncol. 2024; 31(3): 1760-1772.

2023

TS Haddad, L Dobbelsteen, S Kus-Ozturk, R Geene, I Nijman, K Verrijp, N Jamieson, C Wood, S van Lent van Vliet, L Reuvers, S Achouti, N Rutgers, N Brouwer, F Simmer, I Zlobec, A Lugli, ID Nagtegaal. Pseudobudding: Ruptured glands do not represent true tumor buds. J Pathol 2023, 261: 19-27
NPM Brouwer, L Webbink, TS Haddad, N Rutgers, S van Vliet, CS Wood, PWTC Jansen, MW Lafarge, JHW de Wilt, N Hugen, F Simmer, NB Jamieson, DVF Tauriello, VH Koelzer, M Vermeulen, ID Nagtegaal. Transcriptomics and proteomics reveal distinct biology for lymph node metastases and tumour deposits in colorectal cancer. J Pathol 2023, 261:401-412
ID Nagtegaal, E Vink-Borger, CCHJ Kuijpers, E Dekker, NA Shepherd. Incidental findings in the bowel cancer population screening program: other polyps and malignancies – a nation-wide study. Histopathology 2023; 82(2): 254-263
RGS Meester, H van de Schootbrugge-Vandermeer, E Toes-Zoutendijk, AI Kooyker, ECH Breekveldt, L de Jonge, D Nieboer, C Ramakers, MCW Spaander, AJ van Vuuren, EJ Kuipers, FJ van Kemenade, ID Nagtegaal, E Dekker, ME van Leerdam, I Lansdorp-Vogelaar. Faecal occult blood loss accurately predicts future detection of colorectal cancer. A prognostic model. Gut 2023, 72: 101-108
ID Nagtegaal, AF Snoek, P Bult, J Tol, S Siesling, Q Voorham, N Hugen.The value of case reports in rare oncological scenarios: mixed method analysis of colorectal breast cancer metastases. Clin Exp Metas 2023, 40(3): 205-216
van Zwam PH, Vink-BörgerEM, Bronkhorst CM, De Bruine AP, van de Wurff AA, Nagtegaal ID, N Hugen. Prognosis of mucinous colon cancer is determined by histological biomarkers rather than microsatellite instability. Histopath 2023; 82 (2): 314-323
JM Bokhorst, ID Nagtegaal, F Fraggetta, S Vatrano, W Mesker, M Vieth, J van der Laak, F Ciompi. Deep learning for multi-class semantic segmentation enables colorectal cancer detection and classification in digital pathology images. Sci Rep 2023, 13(1): 8398
JM Bokhorst, F Ciompi, S Kus Öztürk, AS Oguz Erdogan, M Vieth, H Dawson, R Kirsch, F Simmer, K Sheahan, A Lugli, I Zlobec, J van der Laak, ID Nagtegaal. Fully automated tumor bud assessment in H&E-stained whole slide images of colorectal cancer. Modern Pathol 2023, 36(9): 100233
JEM Swillens, ID Nagtegaal, S Engels, A Lugli, RPMG Hermens, JAWM van der Laak. Pathologists’ first opinions on barriers and facilitators of computational pathology adoption in oncological pathology: an international study. Oncogene 2023, 42: 2816-2827
AI Kooyker, L de Jonge, E Toes-Zoutendijk, MCW Spaander, AJ van Vuuren, EJ Kuipers, FJ van Kemenade, C Ramakers, E Dekker, ID Nagtegaal, ME van Leerdam, I Lansdorp-Vogelaar. Colorectal Cancer Stage-Distribution at First and Repeat Fecal Immunochemical Test Screening. Clin Gastrol Hepatol 2023, 21(13): 3424-3432
S Kus Ozturk, C Graham Martinez, K Sheahan, D Winter, S Aherne, ÉJ Ryan, CJH van de Velde, CAM Marijnen, GAP Hospers, AGH Roodvoets, M Doukas, D Mens, C Verhoef, RS van der Post, ID Nagtegaal. The relevance of shrinkage versus fragmented response patterns in rectal cancer. Histopath 2023, 83(6): 870-879
I van der Strate, F Kazemzadeh, ID Nagtegaal, D Robbrecht, Y vd Wouw, CS Padilla, S Duijts, M Esteller, FA Greco, N Pavlidis, A Qaseem, P Snaebjornsson, S Veldhuijzen van Zanten, C Loef. International Consensus on the Initial Diagnostic Workup of Cancer of Unknown Primary. Crit Rev Oncol Hematol 2023, 181: 103868
ECH Breekveldt, E Toes-Zoutendijk, MCW Spaander, L. de Jonge, HJ van de Schootbrugge-Vandermeer, AJ van Vuuren, FJ van Kemenade, C Ramakers, E Dekker, ID Nagtegaal, ME van Leerdam, I Lansdorp-Vogelaar. Advanced stage CRC incidence patterns following the phased implementation of the CRC screening program in the Netherlands. EJC 2023, 178: 60-67
A Khan, N Brouwer, F Müller, A Blank, D Soldini , A Noske, E Gaus, S Brandt, ID Nagtegaal, H Dawson, JP Thiran, A Perren, A Lugli, I Zlobec. Computer-assisted diagnosis of lymph node metastases detection in colorectal cancers using transfer learning with an ensemble model. Modern Path 2023, 36(5):100118
DEFWM van Toledo, JEG Ijspeert, MCW Spaander, ID Nagtegaal, ME van Leerdam, I Lansdorp-Vogelaar, E Dekker. Colorectal cancer risk after removal of polyps in fecal immunochemical test based screening. eClinicalMed 2023, 61: 102066
CE Bruggeling, M te Groen, D Garza, F van Heeckeren tot Overlaer, J Krekels, BC Sulaiman, D Karel, A Rulof, AR Schaaphok, D Hornikx, ID Nagtegaal, BE Dutilh, F Hoentjen, A Boleij. Bacterial oncotraits rather than spatial organisation are associated with dysplasia in ulcerative colitis. JCC 2023, 17: 1870-1881
M te Groen, LAAP Derikx, L van Lierop, B Ylstra, F Hoentjen, ID Nagtegaal, F Simmer. Clonal patterns between pouch neoplasia and prior colorectal neoplasia in inflammatory bowel disease patients: an exploratory cohort study. IBD 2023, 29: 1347-1351
HJ van de Schootbrugge-Vandermeer, I Lansdorp-Vogelaar, L de Jonge, AJ van Vuuren, E Dekker, MCW Spaander, C Ramakers, ID Nagtegaal, FJ van Kemenade, ME van Leerdam, E Toes-Zoutendijk. Socio-demographic and cultural factors related to non-participation in the Dutch colorectal cancer screening program. Eur J Cancer 2023, 190: 112942
HJ van de Schootbrugge-Vandermeer, AI Kooyker, PHA Wisse, ID Nagtegaal, HA Geuzinge, E Toes-Zoutendijk, L de Jonge, ECH Breekveldt, AJ van Vuuren, FJ van Kemenade, C Ramakers, E Dekker, I Lansdorp-Vogelaar, MCW Spaander, ME van Leerdam. Interval Post-Colonoscopy Colorectal Cancer Following a Negative Colonoscopy in a FIT-Based Screening Program. Endoscopy 2023, 55(12): 1061-1069
MMHJ van Gelder, YRJ van Rijt-Weetink, A Boleij, J van Drongelen, LJM Smits, N Roeleveld. Use of medication for gastroesophageal reflux during pregnancy and adverse birth outcomes. Neurotoxicology and Teratology 2023, 98:107200
JM Bokhorst, ID Nagtegaal, I Zlobec, H Dawson, K Sheahan, F Simmer, R Kirsch, M Vieth, A Lugli, J Van der Laak, F Ciompi. Semi-supervised learning to automate tumor bud detection in cytokeratin-stained whole-slide images of colorectal cancer. Cancers 2023, 15(7): 2079
L Elze, RS van der Post, JR Vos, AR Mensenkamp, MSC de Hullu, ID Nagtegaal, N Hoogerbrugge, RM de Voer, MJL Ligtenberg. Microsatellite instability in non-colorectal and non-endometrial malignancies in patients with Lynch syndrome. JNCI 2023, 115(7): 853-860
MEW Derks, M te Groen, CP Peters, G Dijkstra, AC de Vries, TEH Romkens, CS Horjus, NK de Boer, ID Nagtegaal, LAAP Derikx, F Hoentjen. Endoscopic and surgical treatment outcomes of colitis-associated advanced colorectal neoplasia: a multicenter cohort study. Int J Surgery, 2023, 109(7): 1961-1969
C Shi, F Webster, ID Nagtegaal. Pathology reporting of gastric endoscopic resections: recommendations from the International Collaboration on Cancer Reporting. Gastroenterology 2023, 164(7): 1039-1043
ECH Breekveldt, E Toes-Zoutendijk, HJ van de Schootbrugge-Vandermeer, L de Jonge, AI Kooyker, MCW Spaander, AJ van Vuuren, FJ van Kemenade, C Ramakers, E Dekker, ID Nagtegaal, ME van Leerdam, I Lansdorp-Vogelaar. Factors Associated With Interval Colorectal Cancer after Negative FIT: Results of Two Screening Rounds in the Dutch FIT-based CRC Screening Program. Int J Cancer 2023, 152(8): 1536-1546
DEFWM van Toledo, ECH Breekveldt, JEG IJspeert, L de Jonge, HJ van de Schootbrugge-Vandermeer, AJ van Vuuren, FJ van Kemenade, C Ramakers, ID Nagtegaal, ME van Leerdam, MCW Spaander, I Lansdorp-Vogelaar, E Toes-Zoutendijk, E Dekker. Advanced serrated polyps as target of screening: detection rate and positive predictive value within a fecal immunochemical test based colorectal cancer screening population. Endoscopy 2023, 55(6): 526-534
Krul MF, Elferink MAG, Kok NFM, Dekker E, Lansdorp-Vogelaar I, Meijer GA, Nagtegaal ID, Breekveldt ECH, Ruers TJM, van Leerdam ME, Kuhlmann KFD. Initial impact of national CRC screening on incidence and advanced colorectal cancer. Clin Gastro Hepatol 2023, 21(3): 797-807
H Ueno, ID Nagtegaal, P Quirke, K Sugihara, Y Ajioka. Tumor deposits in colorectal cancer: Refining their definition in the TNM system. Ann Gastrol Surg 2023, 7: 225-235
S ten Hoorn, L Mol, D Sommeijer, L Nijman, T van der Bosch, TR de Back, B Ylstra, E van Dijk, CJM van Noesel, R Reinten, ID Nagtegaal, M Koopman, CJA Punt, L Vermeulen. Long-term survival update and extended RAS mutational analysis of the CAIRO2 trial: addition of cetuximab to CAPOX/bevacizumab in metastatic colorectal cancer. Clin Colorectal Cancer 2023, 22(1): 67-75
Breekveldt ECH, Toes-Zoutendijk E, de Jonge L, Spaander MCW, Dekker E, van Kemenade FJ, van Vuuren AJ, Ramakers CRB, Nagtegaal ID, van Leerdam ME, Lansdorp-Vogelaar I. Personalized colorectal cancer screening: study protocol of a mixed-methods study on the effectiveness of tailored intervals based on prior f-Hb concentration in a fit-based colorectal cancer screening program (PERFECT-FIT). BMC Gastroenterol 2023: 23(1): 45
L Studer, JM Bokhorst, ID Nagtegaal, I Zlobec, H Dawson, A Fisher. Tumor Budding T-cell Graphs: Assessing the Need for Resection in pT1 Colorectal Cancer Patients. Proc Machine Learning Res 2023; 88: 1-25
B Mlecnik, C Bifulco, G Bindea, F Marliot, A Lugli, FS Ou, I Zlobec, TT Rau, MD Berger, ID Nagtegaal, E Vink-Börger, A Hartmann, C Geppert, J Kolwelter, S Merkel, R Grützmann, M Van den Eynde, A Jouret-Mourin, A Kartheuser, D Léonard, C Remue, JY Wang, P Bavi, MH Roehrl, PS Ohashi, LT Nguyen, SJ Han, HL MacGregor, S Hafezi-Bakhtiari, BG Wouters, GV Masucci, EK Andersson, E Zavadova, M Vocka, J Spacek, L Petruzelka, B Konopasek, P Dundr, H Skalova, K Nemejcova, G Botti, F Tatangelo, P Delrio, G Ciliberto, M Maio, L Laghi, F Grizzi, T Fredriksen, B Buttard, L Lafontaine, D Bruni, C El Sissy, N Haicheur, A Kirilovsky, A Berger, C Lagorce, C Paustian, C Ballesteros-Merino, J Dijkstra, C van de Water, S van Lent- van Vliet, N Knijn,AM Mușină, DV Scripcariu, B Popivanova, M Xu, T Fujita, S Hazama, N Suzuki, H Nagano, K Okuno, T Torigoe, N Sato, T Furuhata, I Takemasa, K Itoh, PS Patel, HH Vora, B Shah, JB Patel, KN Rajvik, SJ Pandya, SN Shukla, Y Wang, G Zhang, Y Kawakami, FM Marincola, PA Ascierto, BA Fox, F Pagès, J Galon. Multicenter International Study of the Consensus Immunoscore for the Prediction of Relapse and Survival in Early-Stage Colon Cancer. Cancers 2023, 15: 418
EAJ de Savornin Lohman, TJJ de Bitter, G Hannink, MFT Wietsma, E Vink-Börger, ID Nagtegaal, TJ Hugh, AJ Gill, N Bhimani, M Seyed Ahadi, RS van der Post, PR de Reuver. Development and external validation of a model to predict overall survival in patients with resected gallbladder cancer: an international multicenter study. Ann Surg 2023, 277(4): e856-e863
LSM Hofste, MJ Geerlings, EJ Kamping, ADH Kouwenhoven, D Von Rhein, EAM Jansen, LM Garms, ID Nagtegaal, RS van der Post, JHW de Wilt, BR Klarenbeek, MJL Ligtenberg. Clinical validity of tumor-informed circulating tumor DNA analysis in patients undergoing surgery of colorectal metastases. Dis Colon Rectum 2023, 66(6): 796-804
KEPE Hermans, F Kazemzadeh, C Loef, RLH Jansen, ID Nagtegaal, PA van den Brandt, LJ Schouten. Risk factors for Cancer of Unknown Primary: a literature review. BMC Cancer 2023, 23: 314
E Soons, PD Siersema, LMA van Lierop, TM Bisseling, MCA van Kouwen, ID Nagtegaal, F Atsma, RS van der Post. Laboratory variation in the grading of dysplasia of duodenal adenomas in familial adenomatous polyposis patients. Familial Cancer 2023, 22(2); 177-186
AR Verhage, ID Nagtegaal, C van der Feen, TFW Wolfs. Through the looking glass: a child with arthralgia, malaise and weight loss. Ped Inf Dis J 2023, 42(7): 629-632
de Reuver PR, van der Post RS. Clinicopathological and Molecular Insights into Gallbladder Cancer. Cancers (Basel). 2023; 15(10): 2728.
Hendricks LAJ, Hoogerbrugge N, Mensenkamp AR, Brunet J, Lleuger-Pujol R, Høberg-Vetti H, Tveit Haavind M, Innella G, Turchetti D, Aretz S, Spier I,Tischkowitz M, Jahn A, Links TP, Olderode-Berends MJW, Blatnik A, Leter EM, Evans DG, Woodward ER, Steinke-Lange V, Anastasiadou VC, Colas C, Villy MC, Benusiglio PR, Gerasimenko A, Barili V, Branchaud M, Houdayer C, Tesi B, Yazicioglu MO, van der Post RS, Schuurs-Hoeijmakers JHM; PTEN Study Group; Vos JR. Cancer risks by sex and variant type in PTEN hamartoma tumor syndrome. J Natl Cancer Inst. 2023; 115(1): 93-103.
Zhou C, Bisseling TM, van der Post RS, Boleij A. The influence of Helicobacter pylori, proton pump inhibitor, and obesity on the gastric microbiome in relation to gastric cancer development. Comput Struct Biotechnol J. 2023; 23: 186-198.
van der Post RS, Bisseling TM, van Dieren JM. Endoscopic surveillance: time for a paradigm shift in hereditary diffuse-type gastric cancer management? Lancet Oncol. 2023; 24(4): 311-312.
van Dieren JM, van der Post RS, Bisseling TM. Shifting perceptions on endoscopic surveillance and timing of prophylactic gastrectomy for hereditary diffuse gastric cancer. Br J Surg. 2023; 110(9): 1028-1029.
Valkema MJ, Vos AM, van der Post RS, Ooms AH, Oudijk L, Eyck BM, Lagarde SM, Wijnhoven BP, Klarenbeek BR, Rosman C, van Lanschot JJB, Doukas M. The effectiveness of neoadjuvant chemoradiotherapy in oesophageal adenocarcinoma with presence of extracellular mucin, signet-ring cells, and/or poorly cohesive cells. J Pathol Clin Res. 2023; 9(4): 322-335.
Hofste LSM, Geerlings MJ, von Rhein D, Rütten H, Westenberg AH, Weiss MM, Gilissen C, Hofste T, van der Post RS, Klarenbeek BR, de Wilt JHW, Ligtenberg MJL; Libic2 collaborators group. Circulating tumor DNA detection after neoadjuvant treatment and surgery predicts recurrence in patients with early-stage and locally advanced rectal cancer. Eur J Surg Oncol. 2023; 49(7): 1283-1290.
Buma AIG, Simmer F, den Braber-Ymker M, Groenen PJTA. Appraisal of the PathoDiscovery: an interactive web-based educational tool for teaching pathophysiology and histopathology. APMIS. 2023; 131(9): 472-479.

2022

ECH Breekveldt, I Lansdorp-Vogelaar, E Toes-Zoutendijk, MCW Spaander, AJ van Vuuren, FJ van Kemenade, C RB Ramakers, E Dekker, ID Nagtegaal, MF Krul, NFM Kok, KFD Kuhlmann, GR Vink, ME van Leerdam, MAG Elferink. Colorectal cancer incidence, mortality, tumour characteristics and treatment before and after introduction of the faecal immunohistochemical testing-based screening programme in the Netherlands: a population-based study. Lancet Gastro Hep 2022; 7(1): 60-68
JF Delattre, AS Oguz Erdogan, R Cohen, Q Shi, JF Emile, J Taieb, J Tabernero, T André, JA Meyerhardt, ID Nagtegaal, M Svrcek. A comprehensive overview of tumour deposits in colorectal cancer: towards a next TNM classification. Cancer Treatm Rev 2022, 103: 102325
MB Loughrey, F Webster, MJ Arends, I Brown, LJ Burgart, C Cunningham, JF Flejou, S Kakar, R Kirsch, M Kojima, A Lugli, C Rosty, K Sheahan, NP West, RH Wilson, ID Nagtegaal. Dataset for pathology reporting of colorectal cancer: recommendations from the International Collaboration on Cancer Reporting (ICCR) . Ann Surg 2022, 275: e549-e561
AK Lam, ID Nagtegaal. Pathology reporting of oesophageal endoscopic resections: Recommendations from the International Collaboration on Cancer Reporting. Gastroenterology 2022, 162 (2): 373-378
E Toes-Zoutendijk, G Vink, ID Nagtegaal, MCW Spaander, E Dekker, ME van Leerdam, S Siesling, I Lansdorp-Vogelaar, MAG Elferink. Impact of COVID-19 and suspension of colorectal cancer screening on incidence and stage distribution of colorectal cancers in the Netherlands. Eur J Cancer 2022; 161: 38-43
LJH Smits, E Vink-Börger, G van Lijnschoten, I Focke-Snieders, RS van der Post, JB Tuynman, NCT van Grieken, ID Nagtegaal. Diagnostic variability in the histopathological assessment of advanced colorectal adenomas and early colorectal cancer in a screening population. Histopathology 2022, 80(5):790-798
ID Nagtegaal, DC Snover. Head to head: should we adopt the term “sessile serrated lesion”? Histopathology 2022, 80: 1019-1025
JEM Swillens, Q Voorham, ID Nagtegaal, R Hermens. Improving interdisciplinary communication: barriers and facilitators for implementation of standardized structured reporting in oncology. JNCCN 2022, 19(13): 64-74
M Swets, C Graham Martinez, S van Lent-van Vliet, A van Tilburg, H Gelderblom, CAM Marijnen, CJH van de Velde, ID Nagtegaal. Microsatellite instability in rectal cancer: what does it mean? A study of two randomized trials and a systematic review of the literature. Histopathology 2022, 81(3): 352-362
L de Jonge, HJ van de Schootbrugge-Vandermeer, ECH Breekveldt, MCW Spaander, AJ van Vuuren, FJ van Kemenade, E Dekker, ID Nagtegaal, ME van Leerdam, I Lansdorp-Vogelaar. Optimal Use of Temporarily Restricted Colonoscopy Capacity in a FIT-based CRC Screening Program: Application during the COVID-19 Pandemic. PlosOne 2022, 17(6): e0270223
ES Zwanenburg, AM Gehrels, VP Bastiaenen, AGJ Aalbers, A Arjona-Sánchez, V Bellato, JDW van der Bilt, AD D’Hoore, E Espinosa-Redondo, CEL Klaver, M Kusters, ID Nagtegaal, B van Ramshorst, HC van Santvoort, GS Sica, P Snaebjornsson, KATGM Wasmann, JHW de Wilt, AM Wolthuis, PJ Tanis. Metachronous peritoneal metastases in patients with pT4b colon cancer: an international multicenter analysis of intraperitoneal versus retroperitoneal ingrowth. Eur J Surg Oncol 2022, 48(9): 2023-2031
SK Öztürk, TS Haddad, I Zlobec, A Lugli, ID Nagtegaal. Attackers and defenders: tumor buds and lymphocytes as morphological biomarkers in colorectal cancer. Diagn Histopath 2022: 28(11): 480-487
V Kryklyva, C Luchini, M Stommel, ID Nagtegaal, LAA Brosens. Detecting Lynch syndrome in pancreatic ductal adenocarcinoma FNA cytology based on cancer history and immunohistochemistry. Gut 2022, 71(7): 1450-1451
V Kryklyva, LAA Brosens, MAJ Marijnissen-van Zanten, MJL Ligtenberg, ID Nagtegaal. Mismatch repair deficiency in early-onset duodenal, ampullary and pancreatic carcinomas is a strong indicator for a hereditary defect. J Pathol Clin Res 2022, 8 (2): 181-190
JEM Swillens, Q Voorham, ID Nagtegaal, R Hermens. Evidence-based selection, development, and testing of a tailored strategy to improve standardized structured reporting in pathology: a multicenter study. Arch Pathol Lab Med 2022, 146 (12): 1496-1507
JEM Swillens, QJM Voorham, RP Akkermans, ID Nagtegaal, RPMG Hermens. Nationwide implementation of a multifaceted tailored strategy to improve uptake of standardized structured reporting in pathology: an effect and process evaluation. Implementation Science 2022, 17(1): 52
B Mlecnik, T Torigoe, G Bindea, B Popivanova, M Xu, T Fujita, S Hazama, N Suzuki, H Nagano, K Okuno, N Sato, T Furuhata, I Takemasa, P Patel, H Vora, B Shah, JB Patel, KN Rajvik, SJ Pandya, SN Shukla, Y Wang, G Zhang, T Yoshino, H Taniguchi, C Bifulco, A Lugli, JJ Lee, I Zlobec, TT Rau, M Berger, ID Nagtegaal, E Vink-Börger, A Hartmann, CI Geppert, J Kolwelter, S Merkel, R Grützmann, M Van den Eynde, A Jouret-Mourin, A Kartheuser, D Léonard, C Remue, J Wang, P Bavi, M Roehrl, PS Ohashi, LT Nguen, SJ Han, HL MacGregor, S Hafezi-Bakhtiari, BG Wouters, GV Masucci, E Andersson, E Zavadova, M Vočka, J Spacek, L Petruželka, B Konopasek, P Dundr, H Skalova, K Němejcová, G Botti, F Tatangelo, P Delrio, G Ciliberto, M Maio, L Laghi, F Grizzi, F Marliot, T Fredriksen, B Buttard, L Lafontaine, P Maby, A Majdi, A Hijazi, C El Sissy, A Kirilovsky, A Berger, C Lagorce, C Paustian, C Ballesteros Merino, J Dijkstra, C Van de Water, S Lent-van Vliet, N Knijn, AM Mușină, D Scripcariu, F Marincola, PA Ascierto, BA Fox, F Pages, Y Kawakami, J Galon. Clinical performance of the consensus Immunoscore in colon cancer in the Asian population from the multicenter international SITC study. Cancers 2022, 14(18): 4346
S Foersch, C Lang-Schwarz, M Eckstein, C Geppert, M Schmitt, B Konukiewitz, T Groll, F Schiktanz, J Engel, Gelitsmann, CG Westhoff, N Frickel, AS Litmeyer, A Grass, P Jank, S Lange, M Tschurtschenthaler, D Wilhelm, W Roth, M Vieth, C Denkert, ID Nagtegaal, W Weichert, M Jesinghaus. pT3 colorectal cancer revisited: a multicentric study on the histological depth of invasion in more than 1000 pT3 carcinomas-proposal for a new pT3a/pT3b subclassification. Br J Cancer 2022, 127(7): 1270-1278
E Latacz, D Höppener, A Bohlok, S Leduc, S Tabariès, C Fernandez Moro, C Lugassy, H Nyström, B Bozoky, G Floris, N Geyer, P Brodt, L Llado, L Van Mileghem, M De Schepper, A Majeed, A Lazaris, P Dirix, Q Zhang, S Petrillo, S Vankerckhove, I Joye, Y Meyer, A Gregorieff, N Ruiz Roig, F Vidal-Vanaclocha, D Larsimont, R Caetano Oliveira, P Metrakos, D Grunhagen, ID Nagtegaal, D Molleví, W Jarnagin, M D’Angelica, A Reynolds, M Doukas, C Desmedt, L Dirix, V Donckier, PM Siegel, R Barnhill, M Gerling, C Verhoef, P Vermeulen. Histopathological growth patterns of liver metastasis: updated consensus guidelines for pattern scoring, perspectives, and recent mechanistic insights. Br J Cancer 2022, 127: 988-1013
C Graham Martínez, S Kus Öztürk, A Al-Kaabi, MJ Valkema, JM Bokhorst, C Rosman, H Rütten, CAP Wauters, M Doukas, JJB van Lanschot, PD Siersema, ID Nagtegaal, RS van der Post. Shrinkage versus fragmentation response in neoadjuvantly treated esophageal adenocarcinoma: significant prognostic relevance. Histopathology 2022, 80: 982-994
C Graham Martinez, Y Barella, S Kuz-Oztürk, M Ansems, MAJ Gorris, S van Vliet, CAM Marijnen, ID Nagtegaal. Immune microenvironment landscape shows treatment-specific differences in rectal cancer patients. Frontiers Immunol 2022, 13: 1011498
SL Gerritse, M Labots, R Ter Heine, H Dekker, D Poel, D Tauriello, ID Nagtegaal, E Van den Hombergh, N Van Erp, HMW Verheul. High-dose intermittent treatment with the multikinase inhibitor sunitinib leads to high intra-tumor drug exposure in patients with advanced solid tumors. Cancers 2022, 14(24): 6061
C Shi, BD Badgwell, HI Grabsch, M Gibson, S Hong, P Kumarasinghe, AK Lam, G Lauwers, M O’Donovan, RS van der Post, L Tang, T Ushiku, M Vieth, CI Selinger, F Webster, ID Nagtegaal. Dataset for reporting Carcinoma of the Stomach in Gastrectomy: recommendations from the International Collaboration on Cancer Reporting. Arch Path Lab Med 2022, 146(9): 1072-1083
DMJ Lambregts, N Bogveradze, LK Blomqvist, E Fokas, J Garcia-Aguilar, B Glimelius, MJ Gollub, T Konishi, CAM Marijnen, ID Nagtegaal, PJ Nilsson, RO Perez, P Snaebjornsson,SA Taylor, DJM Tolan, V Valentini, NP West, A Wolthuis, MJ Lahaye, M Maas, GL Beets, RGH Beets-Tan. Current controversies in TNM for the radiological staging of rectal cancer and how to deal with them: results of a global survey and multidisciplinary expert consensus. Eur Radiol 2022, 32(7): 4991-5003
TJJ de Bitter, PR de Reuver, EAJ de Savornin Lohman, LI Kroeze, E Vink-Börger, S van Vliet, D von Rhein, EAM Jansen, J Verheij, ID Nagtegaal, MJL Ligtenberg, RS van der Post. Towards precision medicine in gallbladder cancer: comprehensive molecular profiling reveals actionable alterations in the majority of patients. NPJ Precision Oncology 2022, 6(1): 83
B Pieplenbosch, JH de Leijer, WA van Dop, ID Nagtegaal, EM Witteman. Thymoma associated autoimmune enteropathy with colonic stricture: a diagnostic and histological challenge. Clin J Gastrol 2022, 15(1): 112-116
EMP Steeghs, GR Vink, MAG Elferink, QJM Voorham, H Gelderblom, ID Nagtegaal, PATH consortium, K Grünberg, MJL Ligtenberg. Nationwide evaluation of mutation-tailored anti-EGFR therapy selection in colorectal cancer patients in daily clinical practice. J Clin Path 2022, 75: 706-711
J Meijer, MAG Elferink, JC van Hoeve, J Buijsen, F van Erning, ID Nagtegaal, PJ Tanis, GR Vink, ML Wumkes, IHJT de Hingh, S Siesling. Impact of the COVID-19 pandemic on colorectal cancer care in the Netherlands: a population-based study. Clin Colorect Cancer 2022, 21(3): e171-e178
TJJ de Bitter, DM Trapman, F Simmer, N Hugen, EAJ de Savornin Lohman, PR de Reuver, J Verheij, ID Nagtegaal, RS. van der Post. Metastasis in the gallbladder: does literature reflect reality? Virchows Archiv 2022, 480: 1201-1209
S Festa, G Zerboni, L Derikx, DG Ribaldone, G Dragoni, C Buskens, E Nieveen van Dijkum, D Pugliese, F Panzuto, I Krela-Kaźmierczak, H Reiss, A Bar-Gil Shitrit, M Chaparro, JP Gisbert, U Kopylov, N Teich, E Vainer, ID Nagtegaal, F Hoentjen, MJ Garcia, R Filip, K Foteinogiannopoulou, I Koutroubakis, M Argollo, RLJ van Wanrooij, H Laja, TL Ortega, M Truyens, T Molnar, E Savarino, A Aratari, C Papi, I Goren.Gastroenteropancreatic Neuroendocrine Neoplasms in Patients with Inflammatory Bowel Disease: An ECCO CONFER Multicentre Case Series. J Crohn Col 2022, 16(6): 940-945
ME de Jong, ID Nagtegaal, S Vos, RS van der Post, Y van Herwaarden, LAAP Derikx, F Hoentjen. Increased colorectal neoplasia risk in patients with inflammatory bowel disease and serrated polyps with dysplasia. Dig Dis Sci 2022, 67(12): 5647-5656
DJ Höppener, JLPL Stook, B Galjart, PMH Nierop, ID Nagtegaal, PB Vermeulen, DJ Grünhagen, C Verhoef, M Doukas. The relationship between primary colorectal cancer and the the histopathological growth patterns of corresponding liver metastases. BMC Cancer 2022: 22(1): 911
JM de Gooyer, FMK Elekonawo, AJA Bremers,OC Boerman, EHJG Aarntzen, PR de Reuver, ID Nagtegaal, M Rijpkema, JHW de Wilt. Multimodal CEA-targeted image-guided cytoreductive surgery for peritoneal metastases of colorectal origin. Nature Comm 2022, 13(1): 2621
DAJJ Driessen, DJJM de Gouw, R Stijns, G Litjens, B Israël, BWJ Philips, JJ Hermans, T Dijkema, BR Klarenbeek, RS van der Post, ID Nagtegaal, ACH van Engen-van Grunsven, LAA Brosens, A Veltien, P Zámecnik, TWJ Scheenen.Validation of in-vivo nodal staging of solid malignancies with USPIO-enhanced MRI: a workflow protocol. Methods and Protocols 2022, 5(2): 24
J Meijer, GR Vink, FPC Sijtsma, J Buijsen, ID Nagtegaal, S Siesling, PJ Tanis, ML Wumkes, IHJT de Hingh, MAG Elferink. Limited impact of the COVID-19 pandemic on colorectal cancer care in the Netherlands in 2020. Int J Col Dis 2022, 37(9): 2013-2020
Drissen MMCM, Vos JR, van der Biessen-van Beek DTJ, van der Post RS, Nagtegaal ID, van Kouwen MCA, Bisseling TM, Hoogerbrugge N. Detection and yield of colorectal cancer surveillance in adults with PTEN hamartoma tumour syndrome. Cancers 2022, 14(16): 4005
JAA Snoek, ID Nagtegaal, S Siesling, HJ van Slooten, N Hugen. The impact of standardized structured reporting of pathology reports for breast cancer in the Netherlands. The Breast 2022, 66: 178-182
Palles C, West HD, Chew E, Galavotti S, Flensburg C, Grolleman JE, Jansen EAM, Curley H, Chegwidden L, Arbe-Barnes EH, Lander N, Truscott R, Pagan J, Bajel A, Sherwood K, Martin L, Thomas H, Georgiou D, Fostira F, Goldberg Y, Adams DJ, van der Biezen SAM, Christie M, Clendenning M, Thomas LE, Deltas C, Dimovski AJ, Dymerska D, Lubinski J, Mahmood K, van der Post RS, Sanders M, Weitz J, Taylor JC, Turnbull C, Vreede L, van Wezel T, Whalley C, Arnedo-Pac C, Caravagna G, Cross W, Chubb D, Frangou A, Gruber AJ, Kinnersley B, Noyvert B, Church D, Graham T, Houlston R, Lopez-Bigas N, Sottoriva A, Wedge D; Genomics England Research Consortium; CORGI Consortium; WGS500 Consortium; Jenkins MA, Kuiper RP, Roberts AW, Cheadle JP, Ligtenberg MJL, Hoogerbrugge N, Koelzer VH, Rivas AD, Winship IM, Ponte CR, Buchanan DD, Power DG, Green A, Tomlinson IPM, Sampson JR, Majewski IJ, de Voer RM. Germline MBD4 deficiency causes a multi-tumor predisposition syndrome. Am J Hum Genet. 2022; 109(5): 953-960.
Monster JL, Kemp LJS, Gloerich M, van der Post RS. Diffuse gastric cancer: Emerging mechanisms of tumor initiation and progression. Biochim Biophys Acta Rev Cancer. 2022; 1877(3): 188719.
Hofste LSM, Geerlings MJ, von Rhein D, Tolmeijer SH, Weiss MM, Gilissen C, Hofste T, Garms LM, Janssen MJR, Rütten H, Rosman C, van der Post RS, Klarenbeek BR, Ligtenberg MJL. Circulating Tumor DNA-Based Disease Monitoring of Patients with Locally Advanced Esophageal Cancer. Cancers (Basel). 2022; 14(18): 4417.
van der Bogt RD, van der Wilk BJ, Oudijk L, Schoon EJ, van Lijnschoten G, Corporaal S, Nieken J, Siersema PD, Bisseling TM, van der Post RS, Quispel R, van Tilburg A, Oostenbrug LE, Riedl RG, Hol L, Kliffen M, Nikkessen S, Eyck BM, van Lanschot JJB, Doukas M, Spaander MCW. Bite-on-bite biopsies for the detection of residual esophageal cancer after neoadjuvant chemoradiotherapy. Endoscopy. 2022; 54(12): 1131-1138.
Al-Kaabi A, Baranov NS, van der Post RS, Schoon EJ, Rosman C, van Laarhoven HWM, Verheij M, Verhoeven RHA, Siersema PD. Age-specific incidence, treatment, and survival trends in esophageal cancer: a Dutch population-based cohort study. Acta Oncol. 2022; 61(5): 545-552.
Garza DR, von Meijenfeldt FAB, van Dijk B, Boleij A, Huynen MA, Dutilh BE. Nutrition or nature: using elementary flux modes to disentangle the complex forces shaping prokaryote pan-genomes. BMC Ecol Evol. 2022; 22(1): 101.
Healthy Brain Study consortium; Aarts E, Akkerman A, Altgassen M, Bartels R, Beckers D, Bevelander K, Bijleveld E, Davidson EB, Boleij A, Bralten J, Cillessen T, Claassen J, Cools R, Cornelissen I, Dresler M, Eijsvogels T, Faber M, Fernández G, Figner B, Fritsche M, Füllbrunn S, Gayet S, van Gelder MMHJ, Gerven MV, Geurts S, Greven CU, Groefsema M, Haak K, Hagoort P, Hartman Y, van der Heijden B, Hermans E, Heuvelmans V, Hintz F, Hollander JD, Hulsman AM, Idesis S, Jaeger M, Janse E, Janzing J, Kessels RPC, Karremans JC, Kleijn W, Klein M, Klumpers F, Kohn N, Korzilius H, Krahmer B, Lange F, Leeuwen JV, Liu H,Luijten M, Manders P, Manevska K, Marques JP, Matthews J, McQueen JM, Medendorp P, Melis R, Meyer A, Oosterman J, Overbeek L, Peelen M, Popma J, Postma G, Roelofs K, van Rossenberg YGT, Schaap G, Scheepers P, Selen L, Starren M, Swinkels DW, Tendolkar I, Thijssen D, Timmerman H, Tutunji R, Tuladhar A, VelingH, Verhagen M, Verkroost J, Vink J, Vriezekolk V, Vrijsen J, Vyrastekova J, Wal SV, Willems R, Willemsen A. Correction: Protocol of the Healthy Brain Study: An accessible resource for understanding the human brain and how it dynamically and individually operates in its bio-social context. PLoS One. 2022; 17(4): e0267071.

2021

F Simmer, RLA van der Linden, B Ylstra, MJL Ligtenberg, RS van der Post, ID Nagtegaal. Multi-focal colorectal cancer – Do intraluminal metastasis occur? Gastroenterology 2021, 160(5): 1853-1855
A Lugli, I Zlobec, M Berger, R Kirsch, ID Nagtegaal. Tumour budding in solid cancers. Nat Rev Clin Oncol 2021, 18: 101-115.
RR Bahadoer, EA Dijkstra, B van Etten, CA Marijnen, H Putter, E Meershoek-Klein Kranenbarg, AG Roodvoets, ID Nagtegaal, R. Beets-Tan, LK Blomqvist, T Fokstuen, BJ. ten Tije, J Capdevila, MP Hendriks, I Edhemovic, AMR Cervantes, PJ Nilsson, B Glimelius, CJH van de Velde, GAP Hospers. Short-course radiotherapy followed by subsequent chemotherapy before surgery in locally advanced rectal cancer. Lancet Oncol 2021, 22(1)29-42
L Elze, AR Mensenkamp, ID Nagtegaal, W van Zelst-Stams, Dutch LS-like study group; RM de Voer, MJL Ligtenberg. Somatic inactivation of a mismatch repair gene is the major cause of mismatch repair-deficient tumors in the absence of a pathogenic germline variant or somatic MLH1-promoter methylation. Gastroenterology 2021, 160: 1414-1416
Groen MT, Derks MEW, Kuijpers CCHJ, Nagtegaal ID, Hoentjen F. Reduction of IBD healthcare during the COVID-19 pandemic: a nationwide retrospective cohort study. Gastroenterology 2021, 160(3): 935-937
Rosty C, Webster F, Nagtegaal ID on behalf of data authoring committee. Pathology Reporting of Colorectal Local Excision specimens: Recommendations from the International Collaboration on Cancer Reporting (ICCR). Gastroenterology 2021, 161(2): 382-387
NPM Brouwer, ID Nagtegaal. Tumor deposits improve staging in colon cancer: what will be the next steps? Annal Oncol 2021, 32(10): 1209-1211
TS Haddad, P Friedl, N Farahani, D Treanor, I Zlobec, ID Nagtegaal. Tutorial: methods for three-dimensional visualization of archival tissue material. Nature Protocols 2021, 16(11): 4945-4962
Brouwer NPM, Lord AC, Terlizzo M, Bateman AC, West NP, Goldin R, Martinez A, Wong NACS, Novelli M, Nagtegaal ID, Brown G. Interobserver Variation in the Histopathological Diagnosis of Tumour Deposits in Rectal Cancer – is the use of histopathological characteristics the way to go? Virchows Archiv 2021, 479: 1111-1118
NDF Georges, B Oberli, T Rau, JA Galván, ID Nagtegaal, H Dawson, A Blank, A Kohler, A Lugli, I Zlobec. Tumour budding and CD8+ T-cells: the “attacker-defender” model in neoadjuvantly treated and untreated rectal cancer Histopath 2021, 78(7): 1009-1018
TS Haddad, A Lugli, S Aherne, V Barresi, B Terris, JM Bokhorst, SF Brockmoeller, M Cuatrecasas, F Simmer, H El-Zimaity, JF Fléjou, D Gibbons, G Cathomas, R Kirsch, T Plato Kuhlmann, C Langner, M Loughrey, R Riddell, A Ristimäki, S Kakar, K Sheahan, D Treanor, J van der Laak, M Vieth, I Zlobec, ID Nagtegaal. Improving tumor budding reporting in colorectal cancer: a Delphi consensus study. Virchows Arch 2021, 479: 459-469
PD Dabir, RS van der Post, ID Nagtegaal. Incidental morphological findings in colorectal adenomas. Histopathology 2021, 78: 348-357
Hugen N, Kanne H, Simmer F, van de Water C, Voorham R, Ho V, Lemmens VEPP, Simons M, Nagtegaal ID. Umbilical metastases: real-world data shows abysmal outcome. Int J Cancer 2021, 149(6): 1266-1273
AI Kooyker, E Toes-Zoutendijk, AWJ Opstal-van Winden, MCW Spaander, E Dekker, M Buskermolen, AJ van Vuuren, EJ Kuipers, FJ van Kemenade, H van Veldhuizen, MGJ Thomeer, ID Nagtegaal, C Ramakers, M van Ballegooijen, HJ de Koning, I Lansdorp-Vogelaar, ME van Leerdam. Colonoscopy-related mortality in a FIT-based colorectal cancer screening program. Clin Gastrol Hepatol 2021; 19: 1418-1425
YJ van Herwaarden, LM Koggel, E Vink-Borger, P Dura, GA Meijer, FM Nagengast, TM Bisseling, ID Nagtegaal. RNF43 mutation analysis in serrated polyposis, sporadic serrated polyps and Lynch syndrome polyps. Histopath 2021, 78(5): 749-758
MK Washington, RM Goldberg, GJ Chang, P Limburg, A Lam, M Salto-Tellez, MJ Arends, ID Nagtegaal, DS Klimstra, M Rugge, P Schirmacher, AJ Lazar, RD Odze, F Carneiro, IA Cree. Diagnosis of digestive system tumours; the WHO classification. Int J Cancer 2021, 148:1040-1050
RM de Voer, IJ Diets, RS van der Post, RDA Weren, EJ Kamping, TJJ de Bitter, RH Verhoeven, E Vink-Borger, A Eijkelenboom, A Mensenkamp, ID Nagtegaal, MCJ Jongmans, MJL Ligtenberg. Comprehensive Analyses of the Clinical and Molecular Landscape of Adolescents and Young Adults with Colorectal Cancer. Clin Gastrol Hepatol 2021, 19(8): 1642-1651
FER Vuik, SAV Nieuwenburg, ID Nagtegaal, EJ Kuipers, MCW Spaander. Clinicopathological characteristics and survival of early onset colorectal cancer. Aliment Pharm Therap 2021, 54(11-12): 1463-1471
C Lang-Schwarz, A Agaimy, R Atreya, C Becker, S Danese, JF Fléjou, N Gaßler, HI Grabsch, A Hartmann, K Kamarádová, AA Kühl, GY Lauwers, A Lugli, ID Nagtegaal, MF Neurath, G Oberhuber, L Peyrin-Biroulet, T Rath, R Riddell, CA Rubio, K Sheahan, H Tilg, V Villanacci, M Westerhoff, M Vieth. Histological Activity Scoring in Chronic Inflammatory Bowel Diseases: Recommendations from the Erlangen International Consensus Conference on Inflammatory Bowel Disease Activity and Presentation of the IBD-DCA Score as a New Index for Histologic Activity Assessment in Ulcerative Colitis and Crohn´s Disease. Virchows Archiv 2021, 478: 581-594
L Studer, A Blank, JM Bokhorst, ID Nagtegaal, I Zlobec, A Lugli, A Fischer, H Dawson. Taking Tumour Budding to the Next Frontier – A post ITBCC 2016 review. Histopathology 2021, 78(4): 476-484
I Zlobec, M Bächli, F Galuppini, MD Berger, HE Dawson, ID Nagtegaal, A Lugli. Refining the ITBCC tumour budding scoring system with a “zero-budding” category in colorectal cancer. Virchows Arch 2021, 479: 1085-1090
Lord AC, Brown G, Abulafi M, Bateman A, Frankel WL, Goldin R, Gopal P, Kirsch R, Loughrey MB, Märkl B, Moran B, Puppa G, Shimada Y, Snaebjornsson P, Svrcek M, Washington K, West NP, Wong NACS, Nagtegaal ID. Histopathological Diagnosis of Tumour Deposits in Colorectal Cancer: A Delphi Consensus Study. Histopathology 2021, 79(2): 168-175
T Bisseling, A van Laarhoven, A Huiijbers, M Brink, R Roverts, B Wagner, ID Nagtegaal, RS van der Post. COVID19 presenting as oesophageal ulceration. Am J Gastrol 2021, 116(2): 421-424
M den Braber-Ymker, MC Vonk, K Grunberg, M Lammens, ID Nagtegaal. Intestinal hypomotility in systemic sclerosis: a histological study into the sequence of events. Clin Rheumology 2021, 40(3): 981-990
SZ Wennmacker, EAJ de Savornin Lohman, NA Hasami, ID Nagtegaal, MA Boermeester, J Verheij, EI Spillenaar Bilgen, JWH Meijer, K Bosscha, JC van der Linden, JJ Hermans, PR de Reuver, JPH Drenth, CJHM van Laarhoven. Overtreatment of non-neoplastic gallbladder polyps due to inadequate routine ultrasound assessment. Dig Surg 2021, 38:73-79
SZ Wennmacker, EAJ de Savornin Lohman, PR de Reuver, JPH Drenth, RS van der Post, ID Nagtegaal, JJ Hermans, CJHM van Laarhoven. Imaging based flowchart for gallbladder polyp evaluation. J Med Imag Rad Sci 2021, 52(1): 68-78
MJ van Amerongen, AM Vos, W van der Woude, ID Nagtegaal, JHW de Wilt, JJ Fütterer, JJ Hermans. Does perfusion computed tomography correlate to pathology in colorectal liver metastases? Plos One 2021, 16(1): e0245764
TJJ de Bitter, LI Kroeze, PR de Reuver, S van Vliet, E Vink-Börger, D von Rhein, EAM Jansen, ID Nagtegaal, MJL Ligtenberg, RS van der Post. Unravelling neuroendocrine gallbladder cancer: Comprehensive clinicopathological and molecular characterization. JCO Precision Oncol 2021, 5:473-484
YJ van Herwaarden, A Madani, RS van der Post, VEPP Lemmens, ID Nagtegaal. Incidental diagnosis of serrated polyp in the appendix warrants colonoscopy to screen for colorectal neoplasia. Br J Surg 2021, 108: e373-e374
T Koëter, RCH Stijns, S van Koeverden, N Hugen, JAG van der Heijden, J Nederend, ID Nagtegaal, M Verheij, HJT Rutten, JHW de Wilt. Poor response and high local recurrence rates of locally advanced mucinous rectal cancer after chemoradiation therapy. Colorectal Dis 2021, 23: 2341-2347
BLM Ykema,ID Nagtegaal, K Kuhlmann, AM van Berkel, ME van Leerdam, on behalf of Dutch T1 CRC Working Group. Adherence to mismatch repair testing guidelines in pT1 colorectal cancer diagnosed before the age of 70 years. Virchows Arch 2021, 479-: 451-457
VP Bastiaenen, AGJ Aalbers, A Arjona-Sánchez, V Bellato, JDW van der Bilt, AD D’Hoore, E Espinosa-Redondo, CEL Klaver, ID Nagtegaal, B van Ramshorst, HC van Santvoort, GS Sica, P Snaebjornsson, KATGM Wasmann, JHW de Wilt, AM Wolthuis, PJ Tanis. Risk of metachronous peritoneal metastases in patients with pT4a versus pT4b colon cancer: an international multicentre cohort study. Eur J Surg Oncol 2021, 47(9): 2405-2413
C Lang-Schwarz, M Angeloni, A Agaimy, R Atreya, C Becker, T Dregelies, JF Fléjou, N Gaßler, H Grabsch, A Hartmann, K Kamarádová, A Kühl, G Lauwers, A Lugli, ID Nagtegaal, MF Neurath, G Oberhuber, T Rath, R Riddell, C Rubio, K Sheahan, V Villanacci, M Westerhoff, F Ferrazzi, M Vieth^.Validation of the Inflammatory Bowel Disease- Distribution, Chronicity, Activity (IBD-DCA) Score for ulcerative colitis and Crohns disease. JCC 2021, 15(10): 1621-1630
RCH Stijns, EWJ Philips, ID Nagtegaal, F Polat, JHW de Wilt, CAP Wauters, P Zamecnik, JJ Fütterer, TWJ Scheenen. USPIO-enhanced MRI of lymph nodes in rectal cancer: a node-to-node comparison with histopathology. Eur J Radiol 2021,138: 109636
DJ Höppener, B Galjart, PMH Nierop, FE Buisman, EP van der Stok, RRJ Coebergh van den Braak, MJ van Amerongen, VP Balachandran, WR Jarnagin, TP Kingham, M Doukas, J Shia, ID Nagtegaal, PB Vermeulen, B Groot Koerkamp, DJ Grünhagen, JHW de Wilt, MI D’Angelica, C Verhoef. Histopathological growth patterns and survival after resection of colorectal liver metastases: an external validation study. JNCI Cancer Spectrum, 2021, 5(3): pkab026
R Taddese, C Belzer, S Aalvink, M de Jonge, ID Nagtegaal, B Dutilh, A Boleij. Production of inactivated Gram-positive and Gram-negative species with preserved cellular morphology and integrity. Microb Meth 2021, 184: 106208
L Keikes, M Kos, XAAM Verbeek, T van Vegchel, ID Nagtegaal, MJ Lahaye, A Méndez Romero, S de Bruijn, HMW Verheul, H Rütten, CJA Punt, PJ Tanis, MGH van Oijen. Conversion of a colorectal cancer guideline into clinical decision tree with assessment of validity. Int J Quality Health Care 2021, 33(2): mzab051
FA Vuijk, C van de Water, S Lent – van Vliet, MJM van der Valk, CJH van de Velde, AL Vahrmeijer, ID Nagtegaal, DE Hilling. Intra-tumoral genomic heterogeneity in rectal cancer: mutational status is dependent on preoperative biopsy depth and location. Cancers 2021, 13: 2271
AK Lam, M Bourke, R Chen, R Fiocca, F Fujishima, S Fujii, M Jansen, P Kumarasinghe, R Langer, S Law, S Meijer, C Muldoon, M Novelli, C Shi, L Tang, ID Nagtegaal. Dataset for the reporting of carcinoma of the oesophagus in resection specimens: recommendations from the International Collaboration on Cancer Reporting. Human Path 2021; 114: 54-65
E Soons, TM Bisseling, RS van der Post, ID Nagtegaal, Y Hazewinkel, MCA van Kouwen, PD Siersema. The Workgroup Serrated Polyps and Polyposis (WASP) for optical diagnosis of colorectal diminutive polyps used with iScan and the impact of the revised World Health Organization (WHO) criteria for diagnosis of colorectal tumors. UEG Journal 2021, 9(7): 819-828
TJJ de Bitter, EAJ de Savornin-Lohman, PR de Reuver, VS Versteeg, E Vink-Börger, J Verheij, ID Nagtegaal, RS van der Post. Quality assessment of gallbladder cancer pathology reports: a Dutch nationwide study. Cancers 2021, 13: 2977
NCM Visser, AAM van der Wurff, C Reijen, PD Dabir, GG Soltani, LS Alcala, D Boll, CM Bronkhorst, PMAJ Geomini, D van Hamont, HADM van Herk, IM de Kievit, PJJM Klinkhamer, H Ngo, BM Pijlman, MPML Snijders, MC Vos, ID Nagtegaal, LFAG Massuger, JMA Pijnenborg, J Bulten. Improving preoperative diagnosis in endometrial cancer using systematic morphological assessment and a small immunohistochemical panel. Human Path 2021, 117: 68-78
Westdorp H, Sweep MWD, Gorris MAJ, Hoentjen F, Boers-Sonderen MJ, van der Post RS, van den Heuvel MM, Piet B, Boleij A, Bloemendal HJ, de Vries IJM. Mechanisms of Immune Checkpoint Inhibitor-Mediated Colitis. Front Immunol. 2021; 12: 768957.
Gullo I, van der Post RS, Carneiro F. Recent advances in the pathology of heritable gastric cancer syndromes. Histopathology. 2021; 78(1): 125-147.
Kuipers H, de Bitter TJJ, de Boer MT, van der Post RS, Nijkamp MW, de Reuver PR, Fehrmann RSN, Hoogwater FJH. Gallbladder Cancer: Current Insights in Genetic Alterations and Their Possible Therapeutic Implications. Cancers (Basel). 2021; 13(21): 5257.
Te Paske IBAW, Garcia-Pelaez J, Sommer AK, Matalonga L, Starzynska T, Jakubowska A; Solve-RD-GENTURIS group,; van der Post RS, Lubinski J, Oliveira C, Hoogerbrugge N, de Voer RM. A mosaic PIK3CA variant in a young adult with diffuse gastric cancer: case report. Eur J Hum Genet. 2021; 29(9): 1354-1358.
Al-Kaabi A, Schoon EJ, Deprez PH, Seewald S, Groth S, Giovannini M, BradenB, Berr F, Lemmers A, Hoare J, Bhandari P, van der Post RS, Verhoeven RHA, Siersema PD. Salvage endoscopic resection after definitive chemoradiotherapy for esophageal cancer: a Western experience. Gastrointest Endosc. 2021; 93(4): 888-898.e1.
van Roessel S, Soer EC, van Dieren S, Koens L, van Velthuysen MLF, Doukas M, Groot Koerkamp B, Fariña Sarasqueta A, Bronkhorst CM, Raicu GM, Kuijpers KC, Seldenrijk CA, van Santvoort HC, Molenaar IQ, van der Post RS, Stommel MWJ, Busch OR, Besselink MG, Brosens LAA, Verheij J; Dutch Pancreatic Cancer Group. Axial slicing versus bivalving in the pathological examination of pancreatoduodenectomy specimens (APOLLO): a multicentre randomized controlled trial. HPB (Oxford). 2021; 23(9): 1349-1359.
Peters Y, Huibertse LJ, Schrauwen RWM, Tan AC, van der Post RS, Siersema PD. Increased risk of Barrett’s oesophagus and related neoplasia in individuals with a positive family history. Eur J Cancer. 2021; 155: 116-126.
Lugli A, Carneiro F, Dawson H, Fléjou JF, Kirsch R, van der Post RS, Vieth M, Svrcek M. The gastric disease of Napoleon Bonaparte: brief report for the bicentenary of Napoleon’s death on St. Helena in 1821. Virchows Arch. 2021; 479(5): 1055-1060.
Al-Kaabi A, van der Post RS, van der Werf LR, Wijnhoven BPL, Rosman C, Hulshof MCCM, van Laarhoven HWM, Verhoeven RHA, Siersema PD. Impact of pathological tumor response after CROSS neoadjuvant chemoradiotherapy followed by surgery on long-term outcome of esophageal cancer: a population-based study. Acta Oncol. 2021; 60(4): 497-504.
Lugli A, Carneiro F, Dawson H, Fléjou JF, Kirsch R, van der Post R, Vieth M, Svrcek M. L’autopsie de Napoléon Bonaparte. Mise au point anatomo-pathologique pour le bicentenaire de la mort de Napoléon I er sur l’île de Sainte-Hélène en 1821 [The autopsy of Napoleon Bonaparte: Anatomo-pathological assessment for the bicentenary of the death of Napoleon I on the island of Saint Helena in 1821]. Ann Pathol. 2021; 41(4): 381-386. French.
Healthy Brain Study consortium; Aarts E, Akkerman A, Altgassen M, Bartels R, Beckers B, Bevelander K, Bijleveld E, Davidson EB, Boleij A, Bralten J, Cillessen T, Claassen J, Cools R, Cornelissen I, Dresler M, Eijsvogels T, Faber M, Fernández G, Figner B, Fritsche M, Füllbrunn S, Gayet S, van Gelder MMHJ, van Gerven M, Geurts S, Greven CU, Groefsema M, Haak K, Hagoort P, Hartman Y, van der Heijden B, Hermans E, Heuvelmans V, Hintz F, den Hollander J, Hulsman AM, Idesis S, Jaeger M, Janse E, Janzing J, Kessels RPC, Karremans JC, de Kleijn W,Klein M, Klumpers F, Kohn N, Korzilius H, Krahmer B, de Lange F, van Leeuwen J,Liu H, Luijten M, Manders P, Manevska K, Marques JP, Matthews J, M. McQueen J, Medendorp P, Melis R, Meyer A, Oosterman J, Overbeek L, Peelen M, Popma J,Postma G, Roelofs K, van Rossenberg YGT, Schaap G, Scheepers P, Selen L, StarrenM, Swinkels DW, Tendolkar I, Thijssen D, Timmerman H, Tutunji R, Tuladhar A,Veling H, Verhagen M, Verkroost J, Vink J, Vriezekolk V, Vrijsen J, VyrastekovaJ, van der Wal S, Willems R, Willemsen A. Protocol of the Healthy Brain Study: An accessible resource for understanding the human brain and how it dynamically and individually operates in its bio-social context. PLoS One. 2021; 16(12): e0260952.
Taddese R, Roelofs R, Draper D, Wu X, Wu S, Swinkels DW, Tjalsma H, Boleij A. Streptococcus gallolyticus Increases Expression and Activity of Aryl Hydrocarbon Receptor-Dependent CYP1 Biotransformation Capacity in Colorectal Epithelial Cells. Front Cell Infect Microbiol. 2021; 11: 740704.
Aarts J, Boleij A, Pieters BCH, Feitsma AL, van Neerven RJJ, Ten Klooster JP, M’Rabet L, Arntz OJ, Koenders MI, van de Loo FAJ. Flood Control: How Milk-Derived Extracellular Vesicles Can Help to Improve the Intestinal Barrier Function and Break the Gut-Joint Axis in Rheumatoid Arthritis. Front Immunol. 2021; 12: 703277.
Bruggeling CE, Garza DR, Achouiti S, Mes W, Dutilh BE, Boleij A. Optimized bacterial DNA isolation method for microbiome analysis of human tissues. Microbiologyopen. 2021; 10(3): e1191.
Becker HEF, Jamin C, Bervoets L, Boleij A, Xu P, Pierik MJ, Stassen FRM, Savelkoul PHM, Penders J, Jonkers DMAE. Higher Prevalence of Bacteroides fragilis in Crohn’s Disease Exacerbations and Strain-Dependent Increase of Epithelial Resistance. Front Microbiol. 2021; 12: 598232.
Boleij A, Fathi P, Dalton W, Park B, Wu X, Huso D, Allen J, Besharati S, Anders RA, Housseau F, Mackenzie AE, Jenkins L, Milligan G, Wu S, Sears CL. G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis. Commun Biol. 2021; 4(1): 585.
Dieleman S, Aarnoutse R, Ziemons J, Kooreman L, Boleij A, Smidt M. Exploring the Potential of Breast Microbiota as Biomarker for Breast Cancer and Therapeutic Response. Am J Pathol. 2021; 191(6): 968-982.

2020

AG Dinmohamed, O Visser, RHA Verhoeven, MWJ Louwman, FH van Nederveen, SM Willems, MAW Merkx, VEPP Lemmens, ID Nagtegaal, S Siesling. Fewer cancer diagnoses during the COVID-19 epidemic in the Netherlands. Lancet Oncology 2020, 21(6): 750-751.
JR Vos, IE Fakkert, JA de Hullu, AM van Altena, AS Sie, H Ouchene, RW Willems, ID Nagtegaal, MCJ Jongmans, AR Mensenkamp, GH Woldringh, J Bulten, EM Leter, CM Kets, M Simons, MJL Ligtenberg, N Hoogerbrugge. Universal tumor DNA BRCA1/2 testing of ovarian cancer: prescreening PARPi treatment and genetic predisposition. JNCI 2020, 112(2): 161-169
Rombouts, AJ, Elferink, MA, Hugen, N, Poortmans, PM, Nagtegaal, ID, de Wilt. Increased risk for second primary rectal cancer after pelvic radiation therapy – a population based study. EJC 2020, 124: 142-151
ID Nagtegaal, RD Odze, D Klimstra, V Paradis, M Rugge, P Schirmacher, MK Washington, F Carneiro, IA Cree. The 2019 WHO classification of tumours of the digestive system. Histopathology 2020, 76: 182-188.
ID Nagtegaal, R Glynne-Jones. How to measure tumor response? A biological explanation of discrepancies. Cancer Treat Rev 2020, 84: 101964
PD Dabir, C Bruggeling, RS van der Post , B Dutilh, N Hoogerbrugge, MJL Ligtenberg, A Boleij, ID Nagtegaal. Microsatellite instability screening in colorectal adenomas to detect Lynch syndrome patients? A systematic review and meta-analysis. Eur J Human Gen 2020, 28 (3): 277-286
R Glynne-Jones, M Hall, ID Nagtegaal. The optimal timing for the interval to surgery after short course preoperative radiotherapy (5 x5 Gy) in rectal cancer- are we too eager for surgery? Cancer Treat Rev 2020, 90: 102104
CEL Klaver, N Bulkmans, P Drillenburg, HI Grabsch, NCT van Grieken, A Karrenbeld, L Koens, I van Lijnschoten, J Meijer, ID Nagtegaal, X Sagaert, K Seldenrijk, MF van Velthuysen, AH Bruggink, PJ Tanis, P Snaebjornsson. Interobserver, intraobserver and interlaboratory variability in reporting of pT4a colon cancer. Virchows Archiv 2020, 476(2): 219-230
JM Bokhorst, A Blank, I Zlobec, H Dawson, A Lugli, M Vieth, LL Rijstenberg, S Brockmöller, M Urbanowicz, JF Fléjou, R Kirsch, F Ciompi, J van der Laak, ID Nagtegaal. Assessment of individual tumor buds using keratin immunohistochemistry: moderate interobserver agreement suggests a role for machine learning. Modern Pathol 2020, 33(5): 825-833
B Mlecnik, C Bifulco, G Bindea, F Marliot, A Lugli, FS Ou, I Zlobec, TT Rau, MD Berger, ID Nagtegaal, E Vink-Börger, A Hartmann, C Geppert, J Kolwelter, S Merkel, R Grützmann, M Van den Eynde, A Jouret-Mourin, A Kartheuser, D Léonard, C Remue, JY Wang, P Bavi, MH . Roehrl, PS Ohashi, LT Nguyen, SJ Han, HL MacGregor, S Hafezi-Bakhtiari, BG Wouters, GV Masucci, EK Andersson, E Zavadova, M Vocka, J Spacek, L Petruzelka, B Konopasek, P Dundr, H Skalova, K Nemejcova, G Botti, F Tatangelo, P Delrio, G Ciliberto, M Maio, L Laghi, F Grizzi, T Fredriksen, B Buttard, L Lafontaine, D Bruni, C El Sissy, N Haicheur, A Kirilovsky, A Berger, C Lagorce, C Paustian, C Ballesteros-Merino, J Dijkstra, C van de Water, S van Lent- van Vliet, N Knijn,AM Mușină, DV Scripcariu, B Popivanova, M Xu, T Fujita, S Hazama, N Suzuki, H Nagano, K Okuno, T Torigoe, N Sato, T Furuhata, I Takemasa, K Itoh, PS Patel, HH Vora, B Shah, JB Patel, KN Rajvik, SJ Pandya, SN Shukla, Y Wang, G Zhang, Y Kawakami, FM Marincola, PA Ascierto, BA Fox, F Pagès, J Galon. Multicenter international SITC study of the consensus Immunoscore for the prediction of survival and response to chemotherapy in Stage III colon cancer. J Clin Oncol 2020, 38(31): 3638-3651
NPM Brouwer, DEW van der Kruijssen, N Hugen, IHJT de Hingh, ID Nagtegaal, RHA Verhoeven, M Koopman, JHW de Wilt. The impact of primary tumor location in synchronous metastasized colorectal cancer: Differences in metastatic sites and survival. Ann Surg Oncol 2020, 27(5): 1580-1588
Lord A, Knijn N, Brown G, Nagtegaal ID. Pathways of spread in rectal cancer: a reappraisal of the true routes to distant metastatic disease. Eur J Cancer 2020, 128, 1-6
JR Vos, IE Fakkert, L Spruijt, RW Willems, S Langenveld, AR Mensenkamp, EM Leter, ID Nagtegaal, MJL Ligtenberg, N Hoogerbrugge. Evaluation of yield and experiences of age-related molecular investigation for heritable and non-heritable causes of mismatch repair deficient colorectal cancer to identify Lynch Syndrome. Int J Cancer 2020, 147(8): 2150-2158
AI Kooyker, E Toes-Zoutendijk, AWJ Opstal-van Winden, MCW Spaander, M Buskermolen, AJ van Vuuren, EJ Kuipers, FJ van Kemenade, C Ramakers, MGJ Thomeer, E Dekker, ID Nagtegaal, HJ de Koning, ME van Leerdam, I Lansdorp-Vogelaar. The second round of the Dutch colorectal screening program: impact of an increased fecal immunochemical test cut-off level on yield of screening. Int J Cancer 2020, 147(4): 1098-1106
E Toes-Zoutendijk, AI Kooyker, AWJ Opstal-van Winden, MCW Spaander, E Dekker, C Ramakers, M Buskermolen, AJ van Vuuren, EJ Kuipers, FJ van Kemenade, MF Velthuysen, MGJ Thomeer, H van Veldhuizen, M van Ballegooijen, ID Nagtegaal, HJ de Koning, ME van Leerdam, I Lansdorp-Vogelaar. Incidence of interval colorectal cancer after negative results from first-round fecal immunochemical screening test, by cut-off value and participants sex and age. Clin Gastrol Hep 2020, 18(7): 1493-1500
Quezada-Marín J, Lam AK, Ochiai A, Odze R, Washington MK, Fukuyama M, Rugge M, Klimstra DS, Nagtegaal ID, Tan PH, Arends MJ, Goldblum JR, Cree IA, Salto-Tellez M. Gastrointestinal tissue-based molecular biomarkers: A practical categorization based on the 2019 WHO classification of epithelial digestive tumors. Histopathology 2020: 77 (3): 340-350
M Simons, F Simmer, J Bulten, MJL Ligtenberg, H Hollema, S van Lent- van Vliet, RM de Voer, JE Kamping, DF van Essen, B Ylstra, LE Schwartz, Y Wang, LF Massuger, ID Nagtegaal, RJ Kurman. Two types of primary mucinous ovarian tumors can be distinguished based on their origin. Modern Pathol 2020, 33(4): 722-733
AGC Bleijenberg, JEG IJspeert, YJ van Herwaarden, S Carballal, M Pellise, G Jung, TM Bisseling,ID Nagtegaal, ME van Leerdam, N van Lelyveld, X Bessa, F Rodríguez-Moranta, BAJ Bastiaansen, W de Klaver, L Rivero, MCW Spaander, JJ Koornstra, L Bujanda, F Balaguer, E Dekker. Personalised surveillance protocol for serrated polyposis syndrome: Results from a prospective 5-year international cohort study. Gut 2020, 69 (1): 112-121
N Hugen, Y Sloot, RT Netea-Maier, C van de Water, JA Smit, ID Nagtegaal, ACH van Engen-van Grunsven. Divergent metastatic patterns between subtypes of thyroid carcinoma: results from the nationwide Dutch pathology registry. J Clin Endo Metabol 2020, 105 (3): 1-8
KATGM Wasmann, CEL Klaver, JDW van der Bilt, ID Nagtegaal, AM Wolthuis, HC van Santvoort, B Ramshorst, A D’Hoore, PJ Tanis, JHW de Wilt. Subclassification of multivisceral resections for T4b colon cancer with relevance for postoperative complications and oncological outcomes. J Gastroint Surgery 2020, 24(9): 2113-2120
A Al-Kaabi, RS van der Post, J Huising, C Rosman, ID Nagtegaal, PD Siersema. Predicting lymph node metastases in cT2N0M0 esophageal cancer: a systematic review of risk factors and meta-analysis of proportions. UEG journal 2020, 8(1): 35-43
SEM van de Ven, LAAP Derikx, ID Nagtegaal, CM van Herpen, W Kievit, R Takes, WJG Melchers, F Hoentjen, LHC Nissen. Laryngeal carcinoma in patients with inflammatory bowel disease: clinical outcomes and risk factors. Inflam Bowel Dis 2020, 26(7): 1060-1067
AG Dinmohamed, M Cellamare, O Visser, L de Munck, MAG Elferink, PJ Westenend, J Wesseling, MJM Broeders, EJ Kuipers, MAW Merkx, ID Nagtegaal, S Siesling.The impact of the temporary suspension of national cancer screening programmes due to the COVID-19 epidemic on the diagnosis of breast and colorectal cancer in the Netherlands. J Hemat Oncol 2020, 13:147
Van der Linden RLA, Rijstenberg LL, van der Linden JC, Vogelaar FJ, Nagtegaal ID, Pruijt J, van der Velde CJH, van den Brule A, Bosscha K. Node negative colorectal cancer patients: assessment of high-risk features on recurrence. Path Res Pract 2020, 216: 153034
de Savornin Lohman EAJ, van der Geest LG, de Bitter TJJ, Nagtegaal ID, van Laarhoven CJHM, van den Boezem P, van der Post CS, de Reuver PR. Reresection in incidental gallbladder cancer: survival and the incidence of residual disease. Ann Surg Oncol 2020, 27(4): 1132-1142
EAJ de Savornin Lohman, TJJ de Bitter, RHA Verhoeven, L van der Geest, J Hagendoorn, N Haj Mohammed, F Daams, HJ Klumpen, TM van Gulik, JI Erdmann, MT de Boer, B Groot Koerkamp, AE Braat, J Verheij, ID Nagtegaal, CJHM van Laarhoven, P van der Boezem, RS van der Post, PR de Reuver. Trends in treatment and survival of gallbladder cancer in the Netherlands; identifying gaps and opportunities from a nation-wide cohort. Cancers 2020: 12(4): 918
DJJM de Gouw, M Rijpkema, TJJ de Bitter, VM Baart, CF Sier, S Hernot, G van Dam, ID Nagtegaal, BR Klarenbeek, C Rosman, RS van der Post. Identifying biomarkers in lymph node metastases and esophageal adenocarcinoma for tumor-targeted imaging. Mol Diag Ther 2020 24(2): 191-200
I Zlobec, H Dawson, A Blank, JM Bokhorst, MD Berger, ID Nagtegaal, A Lugli. Are tumor grade and tumor budding equivalent in colorectal cancer? A retrospective analysis of 771 patients. EJC 2020, 130: 139-145
NPM Brouwer, N Hugen, ID Nagtegaal. More extensive lymphadenectomy in colon cancer; how far are we willing to go for a biomarker? Tech Coloprot 2020, 24:761-764
R Taddese, DR Garza, LN Ruiter, MI de Jonge, C Belzer, S Aalvink, ID Nagtegaal, BE Dutilh, A Boleij. Growth rate alterations of human colorectal cancer cells by 157 gut bacteria. Gut Microbe 2020, 12(1): 1-20
AC Lord, B Moran, M Abulafi, S Rasheed, ID Nagtegaal, M Terlizzo, G Brown. Can extranodal tumour deposits be diagnosed on MRI? Protocol for a multicentre trial (The COMET Trial). BJS Open 2020, 10 (10): e033395
M Verstegen, M Harker, C van de Water, J van Dieren, N Hugen, ID Nagtegaal, C Rosman, RS van der Post. Metastatic pattern in esophageal and gastric cancer: influenced by site and histological subtype. World J Gastro 2020, 26(39): 6037-6046
V Kryklyva, E ter Linde, MJL Ligtenberg, M van der Kolk, M Stommel, JJ Hermans, LD Wood, RH Hruban,GJA Offerhaus, ID Nagtegaal, LAA Brosens. Medullary pancreatic carcinoma due to somatic POLE mutation: a distinctive pancreatic carcinoma with marked long-term survival. Pancreas 2020; 49 (7): 999-1003
Blair VR, McLeod M, Carneiro F, Coit DG, D’Addario JL, van Dieren JM, Harris KL, Hoogerbrugge N, Oliveira C, van der Post RS, Arnold J, Benusiglio PR, Bisseling TM, Boussioutas A, Cats A, Charlton A, Schreiber KEC, Davis JL, Pietro MD, Fitzgerald RC, Ford JM, Gamet K, Gullo I, Hardwick RH, Huntsman DG, Kaurah P, Kupfer SS, Latchford A, Mansfield PF, Nakajima T, Parry S, Rossaak J, Sugimura H, Svrcek M, Tischkowitz M, Ushijima T, Yamada H, Yang HK, Claydon A, Figueiredo J, Paringatai K, Seruca R, Bougen-Zhukov N, Brew T, Busija S, Carneiro P, DeGregorio L, Fisher H, Gardner E, Godwin TD, Holm KN, Humar B,Lintott CJ, Monroe EC, Muller MD, Norero E, Nouri Y, Paredes J, Sanches JM, Schulpen E, Ribeiro AS, Sporle A, Whitworth J, Zhang L, Reeve AE, Guilford P. Hereditary diffuse gastric cancer: updated clinical practice guidelines. Lancet Oncol. 2020; 21(8): e386-e397.
Vos S, van der Post RS, Brosens LAA. Gastric Epithelial Polyps: When to Ponder, When to Panic. Surg Pathol Clin. 2020; 13(3): 431-452.
Kerckhoffs KGP, Liu DHW, Saragoni L, van der Post RS, Langer R, Bencivenga M, Iglesias M, Gallo G, Hewitt LC, Fazzi GE, Vos AM, Renaud F, Yoshikawa T, Oshima T, Tomezzoli A, de Manzoni G, Arai T, Kushima R, Carneiro F, Grabsch HI. Mucin expression in gastric- and gastro-oesophageal signet-ring cell cancer: results from a comprehensive literature review and a large cohort study of Caucasian and Asian gastric cancer. Gastric Cancer. 2020; 23(5): 765-779.
de Gooyer JM, Elekonawo FMK, Bos DL, van der Post RS, Pèlegrin A, Framery B, Cailler F, Vahrmeijer AL, de Wilt JHW, Rijpkema M. Multimodal CEA-Targeted Image-Guided Colorectal Cancer Surgery using 111 In-Labeled SGM-101. Clin Cancer Res. 2020; 26(22): 5934-5942.
de Savornin Lohman E, Duijster J, Groot Koerkamp B, van der Post R, Franz E, Mughini Gras L, de Reuver P. Severe Salmonella spp. Or Campylobacter spp. Infection and the Risk of Biliary Tract Cancer: A Population-Based Study. Cancers (Basel). 2020; 12(11): 3348.
Garza DR, Taddese R, Wirbel J, Zeller G, Boleij A, Huynen MA, Dutilh BE. Metabolic models predict bacterial passengers in colorectal cancer. Cancer Metab. 2020; 8: 3.

2019

SD Crockett, ID Nagtegaal. Terminology, molecular features, epidemiology and management of serrated colorectal neoplasia. Gastroenterology 2019, 157(4): 949-966
CE Sluijter, F van Workum, T Wiggers, C van de Water, O Visser, HJ van Slooten, LIH Overbeek, ID Nagtegaal. Improvement of care in colorectal cancer patients: influence of the introduction of standardized structured reporting for pathology. JCO Clin Cancer Informatics 2019, 3: 1 -12
A Madani, CCHJ Kuijpers, CE Sluijter, JH von der Thusen, K Grunberg, VEPP Lemmens, LIH Overbeek, ID Nagtegaal. Decrease of variation of care in pathology with a national e-learning module. Histopathology 2019, 74(6): 925-932
AJM Rombouts, J Huising, N Hugen, SJ Hogewoning, S Siesling, PMP Poortmans, ID Nagtegaal, JHW de Wilt. Assessment of radiotherapy-associated angiosarcoma after breast cancer treatment in a Dutch population-based Study. JAMA Oncology 2019, 5(2): 267-269
L Beunk, K Brown, ID Nagtegaal, P Friedl, K Wolf. Cancer invasion into musculature: mechanics, molecules and implications. Sem Cell Dev Biol 2019, 93: 36-45
Lord AC, Graham-Martinez C, D’Souza N, Pucher PH, Brown G, Nagtegaal ID. The Significance of Tumour Deposits in Rectal Cancer Following Neo-Adjuvant Therapy: A Systematic Review of the Literature. EJC 2019, 122: 1-8
N D’Souza, MPM De Neree tot Babberich, A d’Hoore, E Tiret, E Xynos, R Beets-Tan, ID Nagtegaal, L Blomqvist, T Holm, B Glimelius, A Lacy, A Cervantes, R Glynne Jones, N West, R Perez, C Quadros, K Lee, T Madiba, S Wexner, JA Garcia, D Sahani, B Moran, P Tekkis, H Rutten, P Tanis, T Wiggers, G Brown. Definition of the Rectum: An International, Expert-Based Delphi Consensus. Ann Surg 2019, 270(6): 955-959
JEM Swillens, CE Sluijter, LIH Overbeek, ID Nagtegaal, RPMG Hermens. Identification of barriers and facilitators in nationwide implementation of standardized structured reporting in pathology: a mixed method study. Virchows Arch 2019, 475(5): 551-561
M Simons, T Bolhuis, TF de Haan, AH Gijsbers, J Bulten, LFAG Massuger, ID Nagtegaal. A novel algorithm for better distinction of primary and metastatic mucinous adenocarcinomas of the ovary. Virchows Archiv 2019, 474(3): 289-296
TJJ de Bitter, R van der Linden, S van Lent-Van Vliet, F Weren, B Ylstra, H van der Linden, J Meijer, N Knijn, C van der Post, F Simmer, ID Nagtegaal. Colorectal metastasis to the gallbladder mimicking a primary gallbladder malignancy: histopathological and molecular characteristics. Histopathology 2019, 75: 394-404
YJ van Herwaarden, S Pape, E Vink Borger, FM Nagengast, P Dura, TM Bisseling, ID Nagtegaal. Reasons why the diagnosis of serrated polyposis syndrome is missed. Eur J Gastro Hepatol 2019, 31(3): 340-344
AGC Bleijenberg, JEG IJspeert, S Carballal, M Pellise, G Jung, YJ van Herwaarden, TM Bisseling,ID Nagtegaal, ME van Leerdam, MCW Spaander, N van Lelyveld, X Bessa, D Rodríguez-Alcalde, BAJ Bastiaansen, L Bujanda, JJ Koornstra, F Rodríguez-Moranta, F Balaguer, E Dekker. Low incidence of advanced neoplasia in serrated polyposis syndrome after total or subtotal colectomy – Results from a 5-year international prospective cohort study. Am J Gastroenterology 2019, 114(9): 1512-1519
N Knijn, C van de Water, S Lent van Vliet, J Meijer, S Riemersma, M Tabar, CJA Punt, L Mekenkamp, F Simmer, ID Nagtegaal. Sequencing of RAS/RAF pathway genes in primary colorectal cancer and matched liver and lung metastases. Applied Cancer Res 2019, 39:9
C Graham-Martinez, N Knijn, M Verheij, ID Nagtegaal, RS van der Post. Tumour Deposits are a significant prognostic factor in Gastric Cancer — A Systematic Review and Meta-Analysis. Histopathology 2019, 74(6): 809-816
AJM Rombouts, N Hugen, R Verhoeven, J Kuiper, PMP Poortmans, JHW de Wilt, ID Nagtegaal. Is preoperative chemoradiation in rectal cancer patients modulated by ACE inhibitors? Results from the Dutch Cancer Registry. Rad Oncol 2019, 138: 86-92
RCH Stijns, EJR de Graaf, CJA Punt, ID Nagtegaal, JJME Nuyttens, E van Meerten, PJ Tanis, IHJT de Hingh, GP van der Schelling, Y Acherman, JWA Leijtens, AJA Bremers, GL Beets, C Hoff, C Verhoef, CAM Marijnen, JHW de Wilt. Chemoradiotherapy followed by organ-sparing transanal endoscopic microsurgery for distal rectal cancer: long-term oncological and functional outcome of the CARTS study. JAMA Surg 2019, 154 (1): 47-54
Y Peters, J Honing, W Kievit, C Kestens, W Pestman, ID Nagtegaal, RS van der Post, PD Siersema. Incidence of progression of persistent nondysplastic Barrett’s esophagus to malignancy. Clin Gastroenterol Hepatol 2019, 17(5): 869-877
ME de Jong, SB van Tilburg, LHC Nissen, W Kievit,  ID Nagtegaal,  F Hoentjen, LAAP Derikx. Long-term risk of advanced neoplasia after colonic low-grade dysplasia in patients with inflammatory bowel disease: a nationwide cohort study. J Crohn Colitis 2019, 13(12): 1485-1491
MCJ van Lanschot, ME van Leerdam, I Lansdorp-Vogelaar, S Doets, ID Nagtegaal, HW Schreurs, R van der Hulst, B Carvalho, E Dekker, AM van Berkel. Yield of one-year surveillance colonoscopy following curative colorectal cancer resection. Clin Gastrol Hepatol 2019, 17(11): 2285-2293
SL Bosch, R Verhoeven, V Lemmens, P Poortmans, JHW de Wilt, ID Nagtegaal. Type of preoperative therapy and stage-specific survival after surgery for rectal cancer: a nationwide population-based cohort study. Virchow Arch 2019, 475(6): 745-755
SZ Wennmacker, AH van Dijk, JHJ Raessens, CJHM van Laarhoven, JPH Drenth, PR de Reuver, ID Nagtegaal. Polyp size of 1 cm is insufficient to discriminate neoplastic and nonneoplastic gallbladder polyps. Surg Endo 2019, 33(5): 1564-1571
V Kryklyva, N Haj Mohammad, FM Morsink, MJL Ligtenberg, GJA Offerhaus, ID Nagtegaal, WW de Leng, LAA Brosens. Pancreatic acinar cell carcinoma is associated with BRCA2 germline mutations: a case report and literature review. Cancer Biol Ther 2019, 20(7): 949-955
DM Riviere, EJM van Geenen, MB van der Kolk, ID Nagtegaal, SA Radema, CJHM van Laarhoven, JJ Hermans. Improving preoperative detection of synchronous liver metastases in pancreatic cancer with combined contrast-enhanced and diffusion weighted MRI. Abd Radiol 2019, 44(5): 1756-1765
NS Baranov, ID Nagtegaal, NCT van Grieken, RHA Verhoeven, QJM Voorham, C Rosman, RS van der Post. Synoptic reporting increases quality of upper gastrointestinal cancer pathology reports. Virchow Arch 2019, 475 (2): 255-259
Geessink, A Baidoshvili, JM Klaase, B Ehteshami Bejnordi, GJS Litjens, GW van Pelt, WE Mesker, ID Nagtegaal, F Ciompi, JAWM van der Laak. Computer aided quantification of intratumoural stroma yields an independent prognosticator in rectal cancer. Cell Oncol 2019, 42 (3): 331-341
NCA Vermeer, MPM de Neree tot Babberich, P Fockens, ID Nagtegaal, GJ Liefers, CJH van de Velde, E Dekker, PJ Tanis, KCMJ Peeters. Referral for surgery and surgical outcomes of non-malignant colorectal polyps: a multicentre study. BJS Open 2019, 3: 687-695
RCH Stijns, EWJ Philips, CAP Wauters, JHW de Wilt, ID Nagtegaal, TWJ Scheenen. Ex-vivo MR-guided pathology to determine number and size of mesorectal lymph nodes to improve lymph node staging in rectal cancer. Invest Radiol 2019, 54(10): 645-652
KATGM Wasmann, CEL Klaver, JDW van der Bilt, ID Nagtegaal, CJA Punt, B van Ramshorst, AM Wolthuis, JHW de Wilt, A D’Hoore, HC van Santvoort, PJ Tanis. Laparoscopic surgery facilitates adjuvant chemotherapy in locally advanced colon cancer with associated survival benefits. Cancer Man Res 2019, 11: 7141-7157
ID Nagtegaal. New in 2019: a preview of the improved bedrock of cancer classification. Colorectal Dis 2019, 21: 5
M Simons, ID Nagtegaal. Response to “novel” nomogram and algorithm do not aid in the distinction of primary versus metastatic mucinous carcinoma of the ovary: letter to the editor. Virchows Arch 2019, 474 (6): 777-778
EEGW ter Voert, L Heijmen, JJA van Asten, AJ Wright, ID Nagtegaal, CJA Punt, JHW de Wilt, HWM van Laarhoven, A Heerschap. Levels of choline-containing compounds in normal liver and liver metastases of colorectal cancer as recorded by ¹H MR spectroscopy. NMR in Biomedicine 2019, 32(1): e4035
AMWM Aarts, SW Duffy, SME Geurts, DP Vulkan, N Houssami, M Zappa, ID Nagtegaal, ALM Verbeek, MJM Broeders. Towards evidence-based breast cancer follow-up intervals: estimates of the preclinical detectable phase of contralateral second breast cancers. The Breast, 2019, 45:70-74
A Halilovic, DI Verwey, A Simons, MJPL Stevens-Kroef, S Vermeulen, J Elsink, BBJ Tops, I Otte-Höller, JAWM van der Laak, C van de Water, OBA Boelens, MS Schlooz-Vries, JR Dijkstra, ID Nagtegaal, J Tol, PHJ van Cleef, PN Span, P Bult. HER2, chromosome 17 polysomy and DNA ploidy status in breast cancer; a translational study. Sci Rep 2019, 9(1): 11679
Mariette C, Carneiro F, Grabsch HI, van der Post RS, Allum W, de Manzoni G; European Chapter of International Gastric Cancer Association. Consensus on thepathological definition and classification of poorly cohesive gastric carcinoma. Gastric Cancer. 2019; 22(1): 1-9.
van der Post RS, Oliveira C, Guilford P, Carneiro F. Hereditary gastric cancer: what’s new? Update 2013-2018. Fam Cancer. 2019; 18(3): 363-367.
Mariette C, Carneiro F, Grabsch HI, van der Post RS, Allum W, de Manzoni G; European Chapter of International Gastric Cancer Association. Correction to: Consensus on the pathological definition and classification of poorly cohesive gastric carcinoma. Gastric Cancer. 2019; 22(2): 421.
Bustraan J, Dijkhuizen K, Velthuis S, van der Post R, Driessen E, van Lith JMM, de Beaufort AJ. Why do trainees leave hospital-based specialty training? A nationwide survey study investigating factors involved in attrition and subsequent career choices in the Netherlands. BMJ Open. 2019; 9(6): e028631.
Metz P, Tjan MJH, Wu S, Pervaiz M, Hermans S, Shettigar A, Sears CL, Ritschel T, Dutilh BE, Boleij A. Drug Discovery and Repurposing Inhibits a Major Gut Pathogen-Derived Oncogenic Toxin. Front Cell Infect Microbiol. 2019; 9: 364.
Butt J, Fernández de Larrea N, Tjalsma H, Roelofs R, Kato I, Martín V, Pérez-Gómez B, Moreno V, Dierssen-Sotos T, Castilla J, Fernández-Tardón G, Amiano P, Salas D, Alguacil J, Jiménez-Moleón JJ, Huerta JM, de Sanjosé S, DelCampo R, Kogevinas M, Pollán M, Pawlita M, Waterboer T, Boleij A, Aragonés N. Antibody responses to flagellin C and Streptococcus gallolyticus pilus proteins in colorectal cancer. Sci Rep. 2019; 9(1): 10847.

2018

M Swets, PJ Kuppen, EJ Blok, H Gelderblom, CJH van de Velde, ID Nagtegaal. Are pathological high risk features in locally advanced rectal cancer a useful selection tool for adjuvant chemotherapy? EJC 2018, 89:1-8
N Knijn, UEM van Exsel, ME de Noo, ID Nagtegaal. The value of intramural vascular invasion in colorectal cancer – a systematic review and meta-analysis. Histopathology 2018, 72:721-728
F Pagès, B Mlecnik, F Marliot, G Bindea, FS Ou, C Bifulco, A Lugli, I Zlobec, TT Rau, MD Berger, ID Nagtegaal, E Vink-Börger, A Hartmann, C Geppert, J Kolwelter, S Merkel, R Grützmann, M Van den Eynde, A Jouret-Mourin, A Kartheuser, D Léonard, C Remue, JY Wang, P Bavi, MHA Roehrl, PS Ohashi, LT Nguyen, SJ Han, HL MacGregor, S Hafezi-Bakhtiari, BG Wouters, GV Masucci, EK Andersson, E Zavadova, M Vocka, J Spacek, L Petruzelka, B Konopasek, P Dundr, H Skalova, K Nemejcova, G Botti, F Tatangelo, P Delrio, G Cilberto, M Maio, L Laghi, F Grizzi, T Fredriksen, B Buttard, M Angelova, A Vasaturo, P Maby, SE Church, HK Angell, L Lafontaine, D Bruni, C El Sissy, N Haicheur, A Kirilovsky, A Berger, C Lagorce, JP Meyers, C Paustian, C Ballesteros-Merino, J Dijkstra, C van de Water, S van Lent- van Vliet, N Knijn, AM Mușină, DV Scripcariu, B Popivanova, M Xu, T Fujita, S Hazama, N Suzuki, H Nagano, K Okuno, T Torigoe, N Sato, T Furuhata, I Takemasa, K Itoh, PS Patel, HH Vora, B Shah, JB Patel, KN Rajvik, SJ Pandya, SN Shukla, Y Wang, G Zhang, Y Kawakami, FM Marincola, PA Ascierto, DJ Sargent, BA Fox, J Galon. International validation of the consensus Immunoscore for the prognostic classification of colon cancer. Lancet, 2018, 391(10135): 2128-2139
TEH Römkens, P Kranenburg, A van Tilburg, C Bronkhorst, ID Nagtegaal, JPH Drenth, F Hoentjen. Assessment of histological remission in ulcerative colitis: discrepancies between daily practice and expert opinion. J Crohn Colitis 2018, 12(4): 425-431
AJM Rombouts, N Hugen, JJP van Beek, PMP Poortmans, JHW de Wilt, ID Nagtegaal. Does pelvic radiation increase rectal cancer incidence? – a systematic review and meta-analysis. Cancer Treatment Reviews 2018, 68:136-144
LHC Nissen, LAAP Derikx, A Jacobs, CM van Herpen, W Kievit, R Verhoeven, E van den Broek, E Bekers, T van den Heuvel, M Pierik, J Rahamat-Langendoen, R Takes, W Melchers, ID Nagtegaal, F Hoentjen. Risk factors and clinical outcomes of head and neck cancer in inflammatory bowel disease: a nationwide cohort study. IBD 2018, 24 (9): 2015-2026
AJM Rombouts, N Hugen, RHA Verhoeven, MAG Elferink, PMP Poortmans, ID Nagtegaal, JHW de Wilt. Tumour Response After Long Interval Comparing 5x5Gy Radiation Therapy with Chemoradiation Therapy in Rectal Cancer Patients. EJSO 2018, 44(7): 1018-1024
NPM Brouwer, ACRK Bos, VEPP Lemmens, PJ Tanis, N Hugen, ID Nagtegaal, JHW de Wilt, RHA Verhoeven. An overview of 25 years of incidence, treatment and outcome of colorectal cancer patients: Results from the Netherlands Cancer Registry. Int J Cancer 2018, 143(11): 2758-2766
N Brouwer, R Stijns, R Verhoeven, V Lemmens, ID Nagtegaal, P Tanis, R Beets-Tan, J Fütterer, JHW de Wilt. Clinical lymph node staging in colorectal cancer; a flip of the coin? EJSO 2018, 44(8): 1241-1246
M Broeders, P Allgood, SW Duffy, S Hofvind, ID Nagtegaal, E Paci, S Moss, L Bucchi. The impact of mammographic screening on incidence of advanced breast cancer in Europe: a literature review. BMC Cancer 2018, 18(1): 860
NCM Visser, AAM van der Wurff, JMA Pijnenborg, LFAG Massuger, J Bulten, ID Nagtegaal. Tissue microarray for scientific biomarkers studies in endometrial cancer. Virchow Archiv 2018, 472(3): 407-413
M den Braber-Ymker, S Heijker, M Lammens, S Croockewit, ID Nagtegaal. Intestinal involvement in amyloidosis is a sequential process. Neurogastrol Mot 2018, e13469
JM Bokhorst, L Rijstenberg, D Goudkade, ID Nagtegaal, J van der Laak, F Compi. Automatic detection of tumor budding in colorectal cancer with deep learning. COMPAY 2018, 11039: 130-138
Siddiqui M, Nagtegaal ID, Santiago I, Knijn N, Berho M, Mimezami A, Roa S, Brown G. What causes liver metastases – lymph nodes or is it something else? Colorectal Dis 2018, 20(S1): 39-42
FAB Grimme, MFJ Seesing, R van Hillegersberg, F van Coevorden, KP de Jong, ID Nagtegaal, C Verhoef, JHW de Wilt. Liver resection for hepatic metastases from soft tissue sarcoma: A nationwide retrospective study. Dig Surg 2018, 25: 1-8
CEL Klaver, KATGM Wasmann, M Verstegen, JDW van der Bilt, ID Nagtegaal, B van Ramshorst, PJ Tanis, AM Wolthuis, HC van Santvoort, JHW de Wilt, A D’Hoore. Postoperative abdominal infections after resection of T4 colon cancer increase the risk of intra-abdominal recurrence. Eur J Surg Oncol 2018, 44:1880-1888
Weren RDA, van der Post RS, Vogelaar IP, van Krieken JH, Spruijt L, Lubinski J, Jakubowska A, Teodorczyk U, Aalfs CM, van Hest LP, Oliveira C, Kamping EJ, Schackert HK, Ranzani GN, Gómez García EB, Hes FJ, Holinski-Feder E,Genuardi M, Ausems MGEM, Sijmons RH, Wagner A, van der Kolk LE, Cats A, Bjørnevoll I, Hoogerbrugge N, Ligtenberg MJL. Role of germline aberrations affecting CTNNA1, MAP3K6 and MYD88 in gastric cancer susceptibility. J Med Genet. 2018; 55(10): 669-674.
van der Post RS, van Dieren J, Grelack A, Hoogerbrugge N, van der Kolk LE, Snaebjornsson P, Lansdorp-Vogelaar I, van Krieken JH, Bisseling TM, Cats A. Outcomes of screening gastroscopy in first-degree relatives of patients fulfilling hereditary diffuse gastric cancer criteria. Gastrointest Endosc. 2018; 87(2): 397-404.e2.
Jans C, Boleij A. The Road to Infection: Host-Microbe Interactions Defining the Pathogenicity of Streptococcus bovis/Streptococcus equinus Complex Members. Front Microbiol. 2018; 9: 603.
Dejea CM, Fathi P, Craig JM, Boleij A, Taddese R, Geis AL, Wu X, De Stefano Shields CE, Hechenbleikner EM, Huso DL, Anders RA, Giardiello FM, Wick EC, Wang H, Wu S, Pardoll DM, Housseau F, Sears CL. Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria. Science. 2018; 359(6375): 592-597.

2017

ID Nagtegaal, N Knijn, N Hugen, T Tot, H Marshall, K Sugihara, H Ueno, P Quirke. Tumor deposits: improving the value of modern staging – including a systematic review and meta-analysis in colorectal cancer. JCO 2017, 35(10): 1119-1127
ID Nagtegaal, HJ Schmoll. What is the role of lymph node metastases in the progression of colorectal cancer? Nat Rev Gastroenterol Hepatol 2017, 14(11): 633-634
JEG IJspeert, A Madani, LIH Overbeek, E Dekker, ID Nagtegaal. Implementation of an e-learning improves the inter-laboratory consistency in the histopathological classification of serrated polyps. Histopathology 2017, 70:929-937
AJM Rombouts, N Hugen, MAG Elferink, T Feuth, P M Poortmans, ID Nagtegaal, JHW de Wilt. The incidence of secondary pelvic tumors after treatment with or without radiation for rectal cancer. Ann Oncol 2017, 28(3): 535-540
E Toes-Zoutendijk, ME van Leerdam, E Dekker, F van Hees, C Penning, G Meijer, I Nagtegaal, MP van der Meulen, AJ van Vuuren, EJ Kuipers, JMG Bonfrer, K Biermann, MGJ Thomeer, H van Veldhuizen, S Kroep, M van Ballegooijen, HJ de Koning, MCW Spaander, I Lansdorp-Vogelaar. The Dutch national FIT-based colorectal screening program: optimizing by real-time monitoring. Gastroenterology 2017, 152(4): 767-775
IJ Diets, ID Nagtegaal, J Loeffen, E Waanders, N Hoogerbrugge, MCJ Jongmans. Childhood neuroendocrine tumors: a descriptive study revealing clues for genetic predisposition. BJC 2017, 116(2): 163-168
A Trinh, F De Sousa E Melo, X Wang, JH de Jong, E Fessler, PJ Kuppen, MS Reimers, M Swets, M Koopman, ID Nagtegaal, M Jansen, GKJ Hooijer, CJ Punt, JP Medema, F Markowetz, L Vermeulen. Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer. Clin Cancer Res 2017, 23(2): 387-398
LAAP Derikx, LJT Smits, S van Vliet, NE Dekker, CM Aalfs, FM Nagengast, ID Nagtegaal, N Hoogerbrugge, F Hoentjen. Colorectal cancer risk in patients with both Lynch syndrome and inflammatory bowel disease. Clin Gastrol Hepatol 2017, 15(3): 454-458
J IJspeert, SAQ Rana, NSS Atkinson, YJ van Herwaarden, BAJ Bastiaansen, ME van Leerdam, S Sanduleanu, TM Bisseling, MCW Spaander, SK Clark, GA Meijer, N van Lelyveld, JJ Koornstra, ID Nagtegaal, JE East, A Latchford, E Dekker. Clinical risk factors for colorectal cancer in patients with serrated polyposis syndrome: a multicenter cohort analysis. Gut 2017, 66(2): 278-284
LHC Nissen, M Pierik, LAAP Derikx, EMGJ de Jong, W Kievit, TRA van den Heuvel, A van Rosendael, EI Plasmeijer, P Dewint, ID Nagtegaal, F Hoentjen, AE van der Meulen – de Jong. Risk factors and clinical outcome in inflammatory bowel diseases patients with melanoma. IBD 2017, 23(11): 2018-2026
AJM Rombouts, I Al-Najami, NL Abbott, A Appelt, G Baatrup, S Bach, A Bhangu, KL Garm Spindler, R Gray, K Handley, M Kaur, E Kerkhof, C Jensenius Kronborg, L Magill, CAM Marijnen, ID Nagtegaal, L Nyvang, FP Peters, P Pfeiffer, C Punt, P Quirke, D Sebag-Montefiore, M Teo, N West, JHW de Wilt. Can we Save the rectum by watchful waiting or TransAnal microsurgery following (chemo) Radiotherapy versus Total mesorectal excision for early REctal Cancer (STAR-TREC study)?: protocol for a multicentre, randomised feasibility study. BMJ Open 2017; 7: e019474
ID Nagtegaal. Never too old to fight cancer? What do we know about colorectal cancer in the elderly? Colorectal Dis 2017: 19(3): 223
A Lugli, R Kirsch, Y Ajioka, F Bosman, G Cathomas, H Dawson, H El Zimaity, JF Fléjou, TP Hansen, S Kakar, C Langner, ID Nagtegaal, G Puppa, R Riddell, A Ristimäki, K Sheahan, T Smyrk, K Sugihara, B Terris, H Ueno, M Vieth, I Zlobec, P Quirke. Recommendations for Reporting Tumor Budding in Colorectal Cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016. Modern Pathology 2017, 30(9): 1299-1311
A Halilovic, JP Bulte, YHA Jacobs, H Braam, PHJ van Cleef, M Schlooz-Vries, JEM Werner, OB Boelens, ID Nagtegaal, JHW de Wilt, P Bult. Brief fixation of core needle biopsies enables same day diagnosis of breast cancer without frustrating assessment of hormone receptor and E-cadherin immunohistochemistry and human epidermal growth factor receptor 2  fluorescence in situ hybridization. J Clin Pathol 2017, 70(9): 781-786
LJW Bosch, G Trooskens, P Snaebjornsson, JC Haan, L Pelosof, M Koopman, J Tol, J Louwagie, L Dehaspe, B Ylstra, H Verheul, M van Engeland, ID Nagtegaal, JG Herman, CJA Punt, W van Criekinge, B Carvalho, GA Meijer. DNA promoter hypermethylation of Decoy Receptor 1 (DCR1) is associated with poor response to irinotecan in colorectal cancer. Oncotarget 2017, 8(38): 63140-63154
SL Bosch, SJ van Rooijen, GMJ Bökkerink, HJW Braam, LAAP Derikx, P Poortmans, CAM Marijnen, ID Nagtegaal, JHW de Wilt. Acute toxicity and surgical complications after pre-operative (chemo)radiation therapy for rectal cancer in patients with inflammatory bowel disease. Rad Oncol 2017, 123:147-153
M Simons, LF Massuger, J Bruls, J Bulten, S Teerenstra, ID Nagtegaal. Relatively poor survival of mucinous ovarian carcinoma in advanced stage: a systematic review and meta-analysis. Int J Gyn Cancer 2017, 27: 651-658
M den Braber-Ymker, M Lammens, MJAM van Putten, ID Nagtegaal. The enteric nervous system and the musculature of the colon are altered in patients with spina bifida and spinal cord injury. Virchow Arch 2017, 470: 175-184
N Hugen, ID Nagtegaal. Distinct metastatic patterns in colorectal cancer patients based on primary tumor location. EJC 2017, 75: 3-4
NCM Visser, C Reijnen, ID Nagtegaal, LFAG Massuger, J Bulten, JMA Pijnenborg. Accuracy of endometrial sampling in endometrial carcinoma: a systematic review and meta-analysis. Obstet Gyn 2017, 130(4): 803-813
M van der Linden, P Bult, ID Nagtegaal, LFAG Massuger, JA de Hullu, J Bulten. Cervical metastasis originating from a primary rectal adenocarcinoma due to a Pagetoid spread. Human Pathol 2017, 68:184-188
NJ Battersby, M Dattani, S Rao,D Cunningham, D Tait,R Adams,BJ Moran, S Khakoo, P Tekkis, S Rasheed, A Mirnezami, P Quirke, NP West, ID Nagtegaal, I Chong, A Sadanandam, K Thomas, M Frost, G Brown. A Rectal Cancer Multicentre Randomised Control Trial Assessing Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker to Stratify Management by Good And Poor Response to Chemoradiotherapy: The TRIGGER Feasibility Study with an Embedded Phase III Design. Trials 2017, 18: 394
NCM Visser, HMJ Werner, C Krakstad, KK Mauland, J Trovik, LFAG Massuger, ID Nagtegaal, JMA Pijnenborg, HB Salvesen, J Bulten, IM Stefansson. Type of vascular invasion predicts metastatic pattern in endometrial cancer. APMIS 2017, 125 (120): 1084-1091
F Ciompi, OGF Geessink, B Ehteshami Bejnordi, GS de Souza, A Baidoshvili, G Litjens, B van Ginneken, ID Nagtegaal, JAWM van der Laak. The importance of stain normalization in colorectal tissue classification with convolutional networks.  IEEE International Symposium on Biomedical Imaging, 2017, 160-163
van der Post RS, Carneiro F. Emerging Concepts in Gastric Neoplasia: Heritable Gastric Cancers and Polyposis Disorders. Surg Pathol Clin. 2017; 10(4): 931-945.
Vogelaar IP, van der Post RS, van Krieken JHJ, Spruijt L, van Zelst-Stams WA, Kets CM, Lubinski J, Jakubowska A, Teodorczyk U, Aalfs CM, van Hest LP, Pinheiro H, Oliveira C, Jhangiani SN, Muzny DM, Gibbs RA, Lupski JR, de Ligt J,Vissers LELM, Hoischen A, Gilissen C, van de Vorst M, Goeman JJ, Schackert HK,Ranzani GN, Molinaro V, Gómez García EB, Hes FJ, Holinski-Feder E, Genuardi M, Ausems MGEM, Sijmons RH, Wagner A, van der Kolk LE, Bjørnevoll I, Høberg-VettiH, van Kessel AG, Kuiper RP, Ligtenberg MJL, Hoogerbrugge N. Unraveling genetic predisposition to familial or early onset gastric cancer using germline whole-exome sequencing. Eur J Hum Genet. 2017; 25(11): 1246-1252.
Couto Furtado Albuquerque M, van Herwaarden Y, Kortman GAM, Dutilh BE, Bisseling T, Boleij A. Preservation of bacterial DNA in 10-year-old guaiac FOBT cards and FIT tubes. J Clin Pathol. 2017; 70(11): 994-996.
Butt J, Werner S, Willhauck-Fleckenstein M, Michel A, Waterboer T, Zörnig I, Boleij A, Dramsi S, Brenner H, Pawlita M. Serology of Streptococcus gallolyticus subspecies gallolyticus and its association with colorectal cancer and precursors. Int J Cancer. 2017; 141(5): 897-904.
Corredoira J, Grau I, Garcia-Rodriguez JF, García-País MJ, Rabuñal R, Ardanuy C, García-Garrote F, Coira A, Alonso MP, Boleij A, Pallares R. Colorectal neoplasm in cases of Clostridium septicum and Streptococcus gallolyticus subsp. gallolyticus bacteraemia. Eur J Intern Med. 2017; 41: 68-73.

2016

N Hugen, G Brown, R Glynne Jones, JH de Wilt, ID Nagtegaal. Advances in care of patients with mucinous colorectal cancer. Nature Rev Clin Oncol 2016, 13(6): 361-369
N Knijn, F Simmer, S Mogk, S Teerenstra, ID Nagtegaal. Perineural invasion is a strong prognostic factor in colorectal cancer: a systematic review. Am J Surg Pathol 2016, 40(1): 103-112
N Knijn, FN van Erning, L Overbeek, CJA Punt, VEPP Lemmens, N Hugen, ID Nagtegaal. Limited effect of lymph node status on metastatic pattern in colorectal cancer patients. Oncotarget 2016, 7(22): 31699-31707
EMV de Cuba, P Snaebjornsson, DAM Heideman, NCT van Grieken, LJW Bosch, RJA Fijneman, E Belt, H Bril, HBAC Stockman, E Hooijberg, CJA Punt, M Koopman, ID Nagtegaal, VHM Coupé, B Carvalho, GA Meijer. Prognostic value of BRAF and KRAS mutation status in stage II and III microsatellite instable colon cancers. Int J Cancer 2016, 138(5): 1139-1145
Tjalma JJ; Garcia-Allende PB; Hartmans E; Terwisscha van Scheltinga AG; Boersma-van Ek W; Glatz J; Koch M; van Herwaarden, YJ; Bisseling TM; Nagtegaal, ID; Timmer-Bosscha H; Koornstra JJ; Karrenbeld A; Kleibeuker JH; GM van Dam; Ntziachristos, V; Nagengast, WB Molecular-guided endoscopy targeting vascular endothelial growth factor A for improved colorectal polyp detection. J Nucl Med 2016, 57(3): 480-485
Derikx LA, Vierdag WA, Kievit W, Bosch S, Hoentjen F, Nagtegaal ID. Is the prevalence of colonic neuroendocrine tumors increased in patients with inflammatory bowel disease? Int J Cancer 2016, 139(3): 535-542
SL Bosch, TA Vermeer, NP West, HAM Swellengrebel, CAM Marijnen, A Cats, C Verhoef, G van Lijnschoten, JHW de Wilt, HJ Rutten, ID Nagtegaal. Histopathological characteristics predict presence of lymph node metastases in ypT0-2 rectal cancer patients after neo-adjuvant chemoradiotherapy; a retrospective multicentre cohort study. Histopathology 2016; 69(5): 839-848
MJ Boers-Sonderen, SF Mulder, ID Nagtegaal, L Derikx, G Wanten, P Mulders, WTA van der Graaf, F Hoentjen , CML van Herpen. Endoscopy of the upper and lower gastrointestinal tract in patients with diarrhea during treatment with vascular endothelial growth factor tyrosine kinase inhibitors. Acta Oncol 2016, 55(4): 444-448
JAM de Ridder, V Lemmens, L Overbeek, ID Nagtegaal, JHW de Wilt. Hepatic resection for metastatic disease; a population-based analysis of trends. Dig Surg 2016, 33(2): 104-113
CCHJ Kuijpers, CE Sluijter, JH von der Thüsen, K Grünberg, MGH van Oijen, PJ van Diest, M Jiwa, ID Nagtegaal LIH Overbeek, SM Willems. Interlaboratory variability in the grading of dysplasia in a nationwide cohort of colorectal adenomas. Histopathology 2016, 69(2): 187-197
CCHJ Kuijpers, CE Sluijter, JH von der Thüsen, K Grünberg, MGH van Oijen, PJ van Diest, M Jiwa, ID Nagtegaal, LIH Overbeek, SM Willems. Interlaboratory variability in the histological grading of colorectal adenocarcinomas in a nationwide cohort. Am J Surg Pathol 2016, 40(8): 1100-1108
M den Braber-Ymker, S Heijker, MM Lammens, ID Nagtegaal. Reliable and practical assessment of the interstitial cells of Cajal. Neurogastrol Motility 2016, 28: 1261-1267
MFJ Seesing, R Tielen, R van Hillegersberg, F van Coevorden, KP de Jong, ID Nagtegaal, C Verhoef, JHW de Wilt. Resection of liver metastases in patients with gastrointestinal stomal tumors in the imatinib era: a nationwide retrospective study. EJSO 2016, 42(9): 1407-1413
CE Sluijter, LRCW van Lonkhuijzen, HJ van Slooten, ID Nagtegaal, LIH Overbeek. The effects of implementing synoptic pathology reporting: a systematic review. Virchow Arch 2016, 468(6): 639-649
LJW Bosch, Y Luo, VV Lao, P Snaebjornsson, G Trooskens, I Vlassenbroeck, S Mongera, W Tang, P Welcsh, J Herman, M Koopman, ID Nagtegaal, CJA Punt, W van Criekinge, GA Meijer, RJ Monnat, B Carvalho, WM Grady. WRN promoter CpG island hypermethylation does not predict a favorable outcome for metastatic colorectal cancer patients treated with irinotecan-based. Clin Cancer Res 2016, 22(18): 1-11
G Litjens, CI Sánchez, N Timofeeva, M Hermsen, ID Nagtegaal, I Kovacs, C Hulsbergen – van de Kaa, P Bult, B van Ginneken, J van der Laak. Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis. Sci Rep 2016, 6: 26286
JAM de Ridder, JHW de Wilt, L Overbeek, V Lemmens, ID Nagtegaal. Incidence and origins of hepatic metastases: an explorative case study of 23154 patients. Oncotarget 2016, 7(34): 55368-55376
AJM Rombouts, N Hugen, MAG Elferink, ID Nagtegaal, JHW de Wilt. Treatment Interval Between Neoadjuvant Chemoradiotherapy and Surgery in Rectal Cancer Patients – a Population Based Study. Annal Surg Oncol, 2016, 23(11): 3593-3601
LHC Nissen, EL Assendorp, RS van de Post, LA Derikx, DJ de Jong, W Kievit, M Pierik, T van den Heuvel, R Verhoeven, LI Overbeek, F Hoentjen, ID Nagtegaal. Impaired gastric cancer survival in inflammatory bowel disease patients. J Gastrointestin Liver Dis 2016, 25(4): 431-440
MP Lutz, JR Zalcberg, M Ducreux, D Arnold, R Glynne-Jones, T Ruers, D Aust, K Bujko, C Cunningham, S Evrard, G Folprecht, JP Gerard, A Habr-Gama, K Haustermans, T Holm, KF Kuhlmann, F Lordick, G Mentha, M Moehler, ID Nagtegaal, A Pigazzi, S Puciarelli, A Roth, H Rutten, HJ Schmoll, H Sorbye, E van Cutsem, J Weitz, F Otto. Second St Gallen EORTC Gastrointestinal Cancer Conference: Controversial issues in the primary treatment of rectal cancer. EJC 2016, 63: 11-24
WAA Borstlap,PJ Tanis ,T Koedam, CAM Marijnen , C Cunningham, E Dekker , M van Leerdam, G Meijer, N van Grieken, ID Nagtegaal, CJA Punt, MGW Dijkgraaf, H De Wilt, G Beets, EJ de Graaf, AAW van Geloven, MF Gerhards, HL van Westreenen, AWH van der Ven, P van Duijvendijk, I de Hingh, JWA Leijtens, C Sietses, EJ Spillenaar-Bilgen, RJCLM Vuylsteke, C Hoff, JWA Burger, WMU van Grevenstein, A Pronk, R Bosker, H Prins, A Smits, S Bruin, DD Zimmerman, LPS Stassen, MS Dunker, M Westerterp, PP Coene , J Stoot, WA Bemelman, JB Tuynman. Rectal preserving treatment for early rectal cancer: A multi-centred randomised trial of radical surgery versus adjuvant chemoradiotherapy after local excision for early rectal cancer. BMC Cancer 2016, 16(1): 513
van der Post RS, Gullo I, Oliveira C, Tang LH, Grabsch HI, O’Donovan M, Fitzgerald RC, van Krieken H, Carneiro F. Histopathological, Molecular, and Genetic Profile of Hereditary Diffuse Gastric Cancer: Current Knowledge and Challenges for the Future. Adv Exp Med Biol. 2016; 908: 371-91.
Vogelaar IP, Ligtenberg MJ, van der Post RS, de Voer RM, Kets CM, JansenTJ, Jacobs L, Schreibelt G; International Gastric Cancer Genetics Group; deVries IJ, Netea MG, Hoogerbrugge N. Recurrent candidiasis and early-onset gastric cancer in a patient with a genetically defined partial MYD88 defect. Fam Cancer. 2016; 15(2):289-96.
van der Post RS, Gullo I, Oliveira C, Tang LH, Grabsch HI, O’Donovan M, Fitzgerald RC, van Krieken H, Carneiro F. Erratum to: Histopathological, Molecular, and Genetic Profile of Hereditary Diffuse Gastric Cancer: Current Knowledge and Challenges for the Future. Adv Exp Med Biol. 2016; 908: E1.
Boleij A, Tack V, Taylor A, Kafatos G, Jenkins-Anderson S, Tembuyser L, Dequeker E, van Krieken JH. RAS testing practices and RAS mutation prevalence among patients with metastatic colorectal cancer: results from a Europe-wide survey of pathology centres. BMC Cancer. 2016; 16(1): 825.
Butt J, Romero-Hernández B, Pérez-Gómez B, Willhauck-Fleckenstein M, Holzinger D, Martin V, Moreno V, Linares C, Dierssen-Sotos T, Barricarte A,Tardón A, Altzibar JM, Moreno-Osset E, Franco F, Requena RO, Huerta JM, Michel A, Waterboer T, Castaño-Vinyals G, Kogevinas M, Pollán M, Boleij A, de Sanjosé S, Del Campo R, Tjalsma H, Aragonés N, Pawlita M. Association of Streptococcus gallolyticus subspecies gallolyticus with colorectal cancer: Serological evidence. Int J Cancer. 2016; 138(7): 1670-9.
Boleij A, Tack V, Taylor A, Kafatos G, Jenkins-Anderson S, Tembuyser L, Dequeker E, van Krieken JH. RAS testing practices and RAS mutation prevalence among patients with metastatic colorectal cancer: results from a Europe-wide survey of pathology centres. BMC Cancer. 2016; 16(1): 825.

2015

N Hugen, CJC van Aart, RHA Verhoeven, VEPP Lemmens, SA Radema, ID Nagtegaal, JHW de Wilt. Colorectal signet-ring cell carcinoma: benefit from adjuvant chemotherapy but a poor prognostic factor. Int J Cancer 2015, 136(2): 333-339
N Hugen, CJH van de Velde, SL Bosch, JJ Fütterer, MAG Elferink, CAM Marijnen, HJ Rutten, JHW de Wilt, ID Nagtegaal.Modern treatment of rectal cancer closes the gap between common adenocarcinoma and the mucinous subtype. Ann Surg Oncol 2015, 22(8): 2669-2676
RDA Weren, MJL Ligtenberg, CM Kets, RM de Voer, L Spruijt, ETP Verwiel, WA van Zelst-Stams, MC Jongmans, C Gilissen, EJ Kamping, ID Nagtegaal, BB Tops, FM Nagengast, A Geurts van Kessel, JH van Krieken, RP Kuiper, N Hoogerbrugge. A germline homozygous mutations in the base-excision repair gene NTHL1 cause adenomatous polyposis and colorectal cancer. Nature Gen 2015, 47(6): 668-671
van Herwaarden YJ, Verstegen MHP, Dura P, Kievit W, Drenth JPH, Dekker E, IJspeert JEG, Hoogerbrugge N, Nagengast FM, Nagtegaal ID, Bisseling TM. Low prevalence of serrated polyposis syndrome in screening populations: a systematic review. Endoscopy 2015, 47(11): 1043-1049
M Chand, T Palmer, L Blomqvist L, ID Nagtegaal, N West, G Brown. Evidence for radiologic and histopathologic prognostic importance of detecting EMVI: recommendations for radiology and histopathology reporting. Colorectal Disease 2015, 17(6): 468-473
N Hugen, F Simmer, LJM Mekenkamp, M Koopman, E van den Broek, JHW de Wilt, CJA Punt, B Ylstra, GA Meijer ID Nagtegaal. Reduced rate of copy number aberrations in mucinous colorectal carcinoma’. Oncotarget 2015, 6(28): 25715-25725
M Simons, ID Nagtegaal, L Overbeek, U Flucke, L Massuger, J Bulten. A patient with a non-invasive mucinous ovarian borderline tumor presenting with late pleural metastases. IJGP 2015, 34(2): 143-150
ID Nagtegaal. Current concepts of colorectal cancer resection pathology. Histopathology 2015, 66 (1); 102–111
JAM de Ridder, N Knijn, JH de Wilt, ID Nagtegaal. Lymphatic invasion is an independent adverse prognostic factor in patients with colorectal liver metastases. Ann Surg Oncol 2015, 22(S3): 638-645
PK Bajpe, A Prahallad, H Horlings, I Nagtegaal, R Beijersbergen, R Bernards. SIRT2 deacetylase modulates the response to multiple targeted therapies through regulation of MEK kinase activity. Oncogene 2015, 34: 531-536
LM Wiltink, RA Nout, M Fiocco, E Meershoek- Klein Kranenbarg, IM Jürgenliemk-Schulz, JJ Jobsen, ID Nagtegaal, HJT Rutten, CJH van de Velde, CL Creutzberg, CAM Marijnen. Second cancers in patients treated with surgery and radiotherapy for rectal or endometrial cancer in the randomized TME, PORTEC-1 and PORTEC-2 trials. J Clin Oncol 2015, 33(15): 1640-1646
N Hugen, M Simons, A Halilović, RS van der Post, AJ Bogers, MAJ Marijnissen-van Zanten, JHW de Wilt, ID Nagtegaal. The molecular background of mucinous carcinoma beyond MUC2. J Pathol: Clin Res 2015; 1(1): 3-17
RM de Voer, MM Hahn,AR Mensenkamp,A Hoischen, C Gilissen, A Henkes, L Spruijt, WA van Zelst-Stams, CM Kets, ET Verwiel, ID Nagtegaal, HK Schackert, A Geurts van Kessel, N Hoogerbrugge, M JL Ligtenberg, RP Kuiper. Deleterious germline BLM Mutations and the Risk for Early-onset Colorectal Cancer. Sci Rep 2015, 5: 14060
AJ Breugom, W van Gijn, EW Muller, Å Berglund, CBM van den Broek, T Fokstuen, H Gelderblom, E Kapiteijn, JWH Leer, CAM Marijnen, H Martijn, E Meershoek – Klein Kranenbarg , ID Nagtegaal, L Påhlman, CJA Punt, H Putter, AGH Roodvoets, HJT Rutten, WH Steup, B Glimelius, CJH van de Velde. Adjuvant chemotherapy for rectal cancer patients treated with preoperative (chemo)radiotherapy and total mesorectal excision: a Dutch Colorectal Cancer Group (DCCG) randomised phase III trial. Ann Oncol 2015, 26(4): 696-701
Nagtegaal ID, Hugen N. The Increasing Relevance of Tumour Histology in Determining Oncological Outcomes in Colorectal Cancer. Curr Colorectal Cancer Rep 2015, 11(5): 259-266
LAAP Derikx, LHC Nissen, JPH Drenth, CM van Herpen, W Kievit, R Verhoeven, PFA Mulders, CA Hulsbergen – van de Kaa, MJ Boers-Sonderen, T van den Heuvel, M Pierik, ID Nagtegaal, F Hoentjen. Better survival of renal cell carcinoma in patients with inflammatory bowel disease. Oncotarget 2015, 6(35): 38336-38347
E van den Broek, MJJ Dijkstra, O Krijgsman, D Sie, JC Haan, JJH Traets, MA van de Wiel, ID Nagtegaal, CJA Punt, B Carvalho, B Ylstra, S Abeln, GA Meijer, RJA Fijneman. High prevalence and clinical relevance of genes affected by chromosomal breaks in colorectal cancer. Plos ONE 2015, 10 (9): e0138141
Bökkerink GM, Buijs EF, de Ruijter W, Rosman C, Sietses C, Strobel R, Heisterkamp J, Nagtegaal ID, Bremers AJ, de Wilt JH. Improved quality of care for patients undergoing an abdominoperineal excision for rectal cancer. Eur J Surg Oncol. 2015; 41(2): 201-207
RDA Weren, R Venkatachalam, JB Cazier, HF Farin, CM Kets, RM de Voer, L Vreede, ETP Verwiel, M van Asseldonk, EJ Kamping, LA Kiemeney, K Neveling, KKH Aben, L Carvajal-Carmona, ID Nagtegaal, HK Schackert, H Clevers, M van de Wetering, IP Tomlinson, MJL Ligtenberg, N Hoogerbrugge, A Geurts van Kessel, RP Kuiper. Germline deletions in the tumor suppressor gene FOCAD are associated with polyposis and colorectal cancer development. J Pathol 2015, 236(2): 155-164
S Venderbosch, S van Lent – van Vliet, F Simmer, M Craenmehr, AFJ de Haan, M Goossens, CJA Punt, M Koopman, ID Nagtegaal. Mitochondrial microsatellite instability in patients with metastatic colorectal cancer. Virchows Arch 2015, 466(5): 495-502
S Venderbosch, S van Lent – van Vliet, AFJ de Haan, MJ Ligtenberg, M Goossens, CJA Punt, M Koopman, ID Nagtegaal. EMAST is associated with a poor prognosis in microsatellite instable colorectal cancer. Plos One 2015, 10(4): e0124538
F Simmer, S Venderbosch, JR Dijkstra, EM Vink-Borger, C Faber, LJ Mekenkamp, M Koopman, AF de Haan, CJ Punt, ID Nagtegaal. MicroRNA-143 is a putative predictive factor for the response to fluoropyrimidine-based chemotherapy in patients with metastatic colorectal cancer. Oncotarget 2015: 22996-23007
T Op de Beeck, A Hommerson, J van Haaren, M vander Heijden, J Davis, P Lucas, L Overbeek, I Nagtegaal. Mining hierarchical Pathology data using inductive logic programming. AIME 2015, LNAI 9105, 76-85
JR Dijkstra, BBJ Tops, ID Nagtegaal, JHJM van Krieken, MJL Ligtenberg. The homogeneous mutation status of a 22 gene panel justifies the use of serial sections of colorectal cancer tissue for external quality assessment. Virchows Archiv 2015, 467 (3): 273-278
J Bruls, M Simons, LI Overbeek, J Bulten, LF Massuger, ID Nagtegaal. A national population-based study provides insight in the origin of malignancies metastatic to the ovary. Virchows Archiv 2015, 467(1): 79-86
M Simons, N Ezendam, J Bulten, ID Nagtegaal, L Massuger. Survival of mucinous ovarian carcinoma and ovarian metastases: a population-based cancer registry study. Int J Gynaecol Cancer 2015, 25 (7): 1208-1215
M Verseveld, EJR de Graaf, C Verhoef, E van Meerten, CJA Punt, IHJT de Hingh, ID Nagtegaal, JJME Nuyttens, CAM Marijnen, JHW de Wilt. Chemoradiation therapy for rectal cancer in the distal rectum followed by organ-sparing transanal endoscopic microsurgery: The CARTS study. Br J Surg 2015, 102(7): 853-860
LHC Nissen, ID Nagtegaal, DJ de Jong, W Kievit, LAAP Derikx, PJTA Groenen, JHJM van Krieken, F Hoentjen. Epstein-Barr virus in Inflammatory Bowel Disease: the spectrum of intestinal lymphoproliferations. J Crohn Colitis 2015, 9(5): 398-403
N Knijn, F Simmer, ID Nagtegaal. Recommendations for reporting histopathology studies: a proposal. Virchows Arch 2015, 466(6): 611-615
N Knijn, ID Nagtegaal. Guidelines for reporting histopathology studies. J Clin Pathol 2015, 68 (2): 173-174
AJ Weickhardt, DS Williams, CK Lee, F Chionh, J Simes, C Murone, K Wilson, MM Parry, K Asadi, A Scott, CJA Punt, ID Nagtegaal, TJ Price, JM Mariadason, NC Tebbutt. Vascular endothelial growth factor D expression is a potential biomarker of bevacizumab benefit in colorectal cancer. BJC 2015, 113 (1): 37-45
J Homan, GM Bökkerink, MJ Aarts, VE Lemmens, G van Lijnschoten, HJ Rutten, JH Wijsman, ID Nagtegaal, JHW de Wilt. Variation in circumferential resection margin: reporting and involvement in the South-Netherlands. EJSO 2015, 41(11): 1485-1492
CJ Punt, ID Nagtegaal, CJ van de Velde, R Beets-Tan, A Cats, N Hoogerbrugge, CA Marijnen. Highlights from the seventh European Multidisciplinary Colorectal Cancer Congress (EMCCC) 2014. Ecancermedicalscience 2015; 9: 497
van der Post RS, Vogelaar IP, Manders P, van der Kolk LE, Cats A, van Hest LP, Sijmons R, Aalfs CM, Ausems MG, Gómez García EB, Wagner A, Hes FJ, Arts N, Mensenkamp AR, van Krieken JH, Hoogerbrugge N, Ligtenberg MJ. Accuracy of Hereditary Diffuse Gastric Cancer Testing Criteria and Outcomes in Patients With a Germline Mutation in CDH1. Gastroenterology. 2015; 149(4): 897-906.e19.
Boleij A, Hechenbleikner EM, Goodwin AC, Badani R, Stein EM, Lazarev MG, Ellis B, Carroll KC, Albesiano E, Wick EC, Platz EA, Pardoll DM, Sears CL. The Bacteroides fragilis toxin gene is prevalent in the colon mucosa of colorectal cancer patients. Clin Infect Dis. 2015; 60(2): 208-15.