Explore the work of our PhD researchers at GUTS. This gallery showcases all completed theses.
D.M.S. Dieleman, May 2026
D.M.S. Dieleman: Exploring novel prognostic and predictive factors in breast cancer. Maastricht University Medical Center+, the Netherlands, May 28th, 2026. Supervising team: M.L. Smidt, H.I. Grabsch, A. Boleij.
L.J.S. Kemp, February 2026
L.J.S. Kemp: Out of touch: Signaling by cell adhesions in diffuse-type gastric cancer. Utrecht University, Utrecht, the Netherlands, February 10th, 2026. Supervising team: B.M.T Burgering, M. Gloerich, R.M. de Voer, R.S. van der Post
V. Kryklyva, January 2026
V. Kryklyva: Guiding the diagnosis in hereditary pancreatic cancer: clinicopathological, histomorphological and molecular insights. Radboud University, Nijmegen, the Netherlands, January 26th, 2026. Supervising team: I.D. Nagtegaal, M.J.L Ligtenberg, L.A.A. Brosens
A. Oguz Erdogan, October 2025
A. Oguz Erdogan: Where do tumor deposits fit in colon cancer. Radboud University, Nijmegen, the Netherlands, October 27th, 2025. Supervising team: I.D. Nagtegaal, F. Doubrava-Simmer
S. Hinić, August 2025
S. Hinić: Exploring cancer predisposition in individuals with multiple primary cancers germline- and tumor genomic profiling. Radboud University, Nijmegen, the Netherlands, August 27th, 2025. Supervising team: N. Hoogerbrugge- van der Linden, M.J.L. Ligtenberg, R.M. de Voer, R.S. van der Post
S. Kus Öztürk, July 2025
S. Kus Öztürk: Refining tumor response in rectal cancer: the role of tumor budding. Radboud University, Nijmegen, the Netherlands, July 2nd, 2025. Supervising team: I.D. Nagtegaal, J.A.W.M. van der Laak, A. Lugli
L. Elze, November 2024
L. Elze: Mismatch repair and homologuous recombination repair deficiencies in genetic tumor risk syndromes – steps towards improved diagnostics and treatment guidance. Radboud University, Nijmegen, the Netherlands, November 7th, 2024. Supervising team: N. Hoogerburgge, R.S. van der Post, M.J.L. Ligtenberg, R. de Voer
N.P.M. Brouwer, September 2024
N.P.M. Brouwer: The outer space principle in colorectal cancer: Can rocket science explain tumor deposits? Radboud University, Nijmegen, the Netherlands, September 20th, 2024. Supervising team: I.D. Nagtegaal, J.H.W. de Wilt, N. Hugen, F. Simmer
J-M. Bokhorst, May 2024
J-M. Bokhorst: Hidden in plain sight. Automatic detection of tumor budding in digital pathology images of colorectal cancer. Radboud University, Nijmegen, the Netherlands, May 7th, 2024. Supervising team: I.D. Nagtegaal, J.A.W.M. van der Laak, A. Lugli, F. Ciompi
T.S. Haddad, May 2024
T.S. Haddad: Tumor budding: a dive into the edge of colorectal cancer invasion. Radboud University, Nijmegen, the Netherlands, May 7th, 2024. Supervising team: I.D. Nagtegaal, J.A.W.M. van der Laak, A. Lugli, F. Simmer
J. Aarts, April 2024
J. Aarts: Exploring new therapeutic approached in mouse models of rheumatoid arthritis. Lessons learned from the joint and gut. Radboud University, Nijmegen, the Netherlands, April 10th , 2024. Supervising team: P van der Kraan, A. Boleij, M. Coenders, F. van de Loo
C. Graham-Martinez, July 2023
C. Graham-Martinez: Unravelling the pathological and biological aspects of tumour response in rectal cancer. Radboud University, Nijmegen, the Netherlands, July 7th, 2023. Supervising team: I.D. Nagtegaal, R.S. van der Post, C.A.M. Marijnen
L. Hofste, May 2023
L. Hofste: The role of ctDNA-based disease monitoring in treatment of patients with surgically resectable gastrointestinal malignancies. Radboud University, Nijmegen, the Netherlands, May 12th, 2023. Supervising team: M.J.L. Ligtenberg, B.R. Klarenbeek, R.S. van der Post.
M. te Groen, April 2023
M. te Groen: Advanced neoplasia in inflammatory bowel disease; prediction, surveillance and management. Radboud University, Nijmegen, the Netherlands, April 4th, 2023. Supervising team: J. Drenth, F. Hoentjen, I.D. Nagtegaal, L.A.A.P. Derikx
E. Soons, April 2023
E. Soons: Challenging beliefs and exploring new modalities for clinical management of gastrointestinal adenomas. Radboud University, Nijmegen, the Netherlands, April 18th, 2023. Supervising team: P.D. Siersema, R.S. van der Post, M. van Kouwen, T. Bisseling
C.E. Bruggeling, February 2023
C.E. Bruggeling: Bacterial biofilms in early colon carcinogenesis: a study in Lynch syndrome and ulcerative colitis. Radboud University, Nijmegen, the Netherlands, February 14th, 2023. Supervising team: A. Boleij, I.D. Nagtegaal, B.E. Dutihl
A. Al-Kaabi, September 2022
A. Al-Kaabi: The changing epidemiology and therapeutic spectrum of esophageal cancer. Radboud University, Nijmegen, the Netherlands, September 29th, 2022. Supervising team: P.D. Siersema, R.S. van der Post, R. Verhoeven
R. Taddese, September 2022
R. Taddese: Superheroes or villains? Interactions of gut bacteria with colorectal cancer. Radboud University, Nijmegen, the Netherlands, September 16th, 2022. Supervising team: A. Boleij, I.D. Nagtegaal, B.E. Dutihl
J.E.M. Swillens, September 2022
J.E.M. Swillens: Implementation of digital pathology applications for standardization in clinical practice. Radboud University, Nijmegen, the Netherlands, September 16th, 2022. Supervising team: R. Hermens, I.D. Nagtegaal, Q. Voorham
A. Halilovic, May 2022
A. Halilovic: Assessment and significance of tumor specific and microenvironmental factors in breast cancer. Radboud University, Nijmegen, the Netherlands, May 31st, 2022. Supervising team: I.D. Nagtegaal, I.J. de Vries, P. Bult
T.J.J. de Bitter, May 2022
T.J.J. de Bitter: Gallbladder cancer: clinicopathological and molecular insights into a rare tumor. Radboud University, Nijmegen, the Netherlands, May 18th, 2022. Supervising team: I.D. Nagtegaal, R.S. van der Post, M.J.L. Ligtenberg, P.R. de Reuver
Y.J. van Herwaarden, January 2022
Y.J. van Herwaarden: Serrated polyposis syndrome: a multidisciplinary approach. Radboud University, Nijmegen, the Netherlands, January 20th, 2022. Supervising team: J.P.H. Drenth, I.D. Nagtegaal, T. Bisseling, N. Hoogerbrugge
E.A.J de Savornin Lohman, July 2021
E.A.J de Savornin Lohman: Diagnosis and treatment of gallbladder cancer: an overview of contemporary practice. Radboud University, Nijmegen, the Netherlands, July 8th, 2021. Supervising team: R.S. van der Post, I.D. Nagtegaal, K. van Laarhoven, P.R. de Reuver
D. de Gouw, March 2021
D. de Gouw: Response assessment after neoadjuvant therapy in esophageal cancer. Towards personalised treatment. Radboud University, Nijmegen, the Netherlands, March 9th, 2021. C. Rosman, B.R. Klarenbeek, M. Rovers, R.S. van der Post
R.L.A. van der Linden, January 2021
R.L.A. van der Linden: Better recognition of regional and distant metastases in colorectal cancer. Radboud University, Nijmegen, the Netherlands, January 28th, 2021. Supervising team: I.D. Nagtegaal, K. Bosscha
M. Simons, November 2020
M. Simons: Perspectives on mucinous ovarian carcinomas: from cell of origin to clinical implications. Radboud University, Nijmegen, the Netherlands, November 2nd, 2020. Supervising team: I.D. Nagtegaal, H. Bulten, L. Massuger
D.R. Garza, September 2020
D.R. Garza: Exploring microbial ecology and evolution with genome scale metabolic models. Radboud Univesrity, Nijmegen, the Netherlands, September 30th, 2020. Supervising team: A. Boleij, B. Dutihl, M. Huijnen
A.J.M. Rombouts, September 2020
A.J.M. Rombouts: Radiotherapy and rectal cancer: benefits and harms. Radboud University, Nijmegen, the Netherlands, September 2nd, 2020. Supervising team: I.D. Nagtegaal, J.H.W. de Wilt, N. Hugen
N.C.M. Visser, January 2020
N.C.M. Visser: Early recognition of high-risk endometrial carcinomas. Radboud University, Nijmegen, the Netherlands, January 23rd, 2020. I.D. Nagtegaal, L. Massuger, H. Bulten, H. Pijnenburg
M. den Braber-Ymker, October 2019
M. den Braber-Ymker: Secondary motility disorders: clues for a better diagnosis. University Twente, Enschede, the Netherlands, October 31st, 2019. Supervising team: I.D. Nagtegaal, M. Lammens, M.J. van Putten
N. Knijn, October 2018
N. Knijn: Pathways of dissemination in colorectal cancer. Radboud University, Nijmegen, the Netherlands, October 10th, 2018. Supervising team: I.D. Nagtegaal, C.J.A. Punt
L.H.C. Nissen, May 2018
L.H.C. Nissen: Malignancies in Inflammatory Bowel Diseases. Radboud University, Nijmegen, the Netherlands, May 29th, 2018. Supervising team: J.P.H. Drenth, F. Hoentjen, I.D. Nagtegaal
S.L. Bosch, March 2018
S.L. Bosch: Clinical and pathological aspects of modern rectal cancer management. Radboud University, Nijmegen, the Netherlands, March 2nd, 2018. Supervising team: I.D. Nagtegaal, J.H.W. de Wilt
J.A.M. de Ridder, May 2017
J.A.M. de Ridder: Incidence, prognostic factors and treatment of liver metastases. Radboud University, Nijmegen, the Netherlands, May 19th, 2017. Supervising team: I.D. Nagtegaal, J.H.W. de Wilt
L.A.A.P. Derikx, January 2017
L.A.A.P. Derikx: Solid intra- and extraintestinal malignancies in inflammatory bowel disease. Radboud University, Nijmegen, the Netherlands, January 17th, 2017. Supervising team: J.P.H. Drenth, F. Hoentjen, I.D. Nagtegaal
N. Hugen: Clinical and biological aspects of mucinous colorectal cancer. Radboud University, Nijmegen, the Netherlands, January 7th, 2016. Supervising team: I.D. Nagtegaal, J.H.W. de Wilt
S. Venderbosch, November 2015
S. Venderbosch: Outcome parameters in metastatic colorectal cancer. University of Amsterdam, Amsterdam, the Netherlands, November 26th, 2015. Supervising team: C.J.A. Punt, I.D. Nagtegaal
J.C. Haan, March 2014
J.C. Haan: Analysis of chromosomal copy number aberrations in gastrointestinal cancer. Free University, Amsterdam, the Netherlands, March 17th, 2014. Supervising team: G.A. Meijer, B. Ylstra, C.J.A. Punt, I.D. Nagtegaal
J.M. Mekenkamp, April 2013
J.M. Mekenkamp: Studies in colorectal cancer metastases: implications for clinical practice. Radboud University, Nijmegen, the Netherlands, April 16th, 2013. Supervising: I.D. Nagtegaal, C.J.A. Punt
J. Tol, June 2010
J. Tol: Targeted therapy in metastatic colorectal cancer. Radboud University, Nijmegen, the Netherlands, June 16th, 2010. Supervising team: J.H.J.M van Krieken, C.J.A Punt, I.D. Nagtegaal
M.J.E.M. Gosens, September 2008
M.J.E.M. Gosens: Pathological and biological aspects of therapy in colorectal cancer. Radboud University, Nijmegen, the Netherlands, September 10th, 2008. Supervising team: J.H.J.M. van Krieken, I.D. Nagtegaal, H. Rutten, A.J. van den Brule
M. Berkhout, October 2007
M. Berkhout: Familial Adenomatous Polyposis: carcinogenesis in the small bowel. Radboud University, Nijmegen, the Netherlands, October 2nd, 2007. Supervising team: F. Nagengast, J.H.J.M. van Krieken, I.D. Nagtegaal
R.S. van der Post
R.S. van der Post: Familial gastric cancer: Clinicopathological and molecular characteristics. Radboud University, Nijmegen, the Netherlands, December 21st, 2017. Supervising team: J.H.J.M. van Krieken, N. Hoogerbrugge-van der Linden, M.J.L. Ligtenberg
A. Boleij,
A. Boleij: Streptococcus Gallolyticus and colorectal cancer: Explorations at the Host-Pathogen Interface. Radboud University, Nijmegen, the Netherlands, January 10th, 2012. Supervising team: D.W. Swinkels, H. Tjalsma
F. Doubrava-Simmer, December 2003
F. Simmer: RNA interference in Caenorhabditis elegans. Mechanism and application. University of Utrecht, the Netherlands, December 15th, 2003. Supervising team: R.H.A. Plasterk.
I.D. Nagtegaal, June 2002
I.D. Nagtegaal: Pathological aspects of rectal carcinoma. Studies from the RT+TME trial. University of Leiden, the Netherlands, June 25th, 2002. Supervising team: C.J.H van de Velde, J.H.J.M. van Krieken.
